Skip to main content

Lomerizine

ADVERTISEMENT
Identification
Molecular formula
C28H32ClN2O4
CAS number
101477-54-7
IUPAC name
2-[3-(4-chlorophenyl)propyl]-6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium;4-hydroxy-4-oxo-but-2-enoate
State
State

At room temperature, Lomerizine is a solid. It is typically found in a crystalline powder form.

Melting point (Celsius)
149.00
Melting point (Kelvin)
422.15
Boiling point (Celsius)
312.00
Boiling point (Kelvin)
585.15
General information
Molecular weight
524.02g/mol
Molar mass
524.0210g/mol
Density
1.2000g/cm3
Appearence

Lomerizine appears as an off-white to yellowish crystalline powder. It is typically handled in a solid form at room temperature.

Comment on solubility

Solubility Characteristics

The compound 2-[3-(4-chlorophenyl)propyl]-6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium;4-hydroxy-4-oxo-but-2-enoate exhibits intriguing solubility properties that are worth noting.


Key Points on Solubility:

  • Aqueous Solubility: Generally, compounds with complex structures and multiple functional groups, such as this one, can demonstrate variable solubility in water.
  • Organic Solvents: The presence of hydrophobic aromatic rings may enhance solubility in organic solvents like ethanol, chloroform, and dimethyl sulfoxide (DMSO).
  • pH Dependence: The ionization state of this compound can significantly affect its solubility. Changes in pH can lead to variations in solubility due to the ionization of functional groups.
  • Temperature Sensitivity: Solubility can also be temperature dependent; typically, increasing the temperature can increase solubility for many organic compounds.

In summary, the solubility of this compound is influenced by multiple factors, including solvent type, pH conditions, and temperature. Understanding these variables can be critical for applications in organic synthesis and drug formulation, where optimal solubility is essential.

Interesting facts

Interesting Facts about 2-[3-(4-chlorophenyl)propyl]-6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium; 4-hydroxy-4-oxo-but-2-enoate

This complex organic compound, known for its multifaceted structure, offers a wealth of intriguing insights into its potential applications and properties. Here are a few key points to consider:

  • Pharmacological Potential: This compound possesses a tetrahydroisoquinoline core, which is often associated with various biological activities, making it a subject of interest for medicinal chemistry. Compounds within this class have shown promise as antidepressants, analgesics, and antioxidants.
  • Chlorophenyl Substituents: The presence of a 4-chlorophenyl group is significant for enhancing molecular interactions. This halogen can influence the compound's binding affinity to biological targets, potentially increasing its efficacy in therapeutic contexts.
  • Dimethoxy Groups: The 6,7-dimethoxy substituents play a pivotal role in the compound's electronic properties, contributing to its ability to interact with various biological systems. Such modifications can lead to improved lipophilicity and affect bioavailability.
  • Synthetic Chemistry: The synthesis of this compound showcases the ingenuity of contemporary organic chemistry, often involving multi-step processes that integrate various chemical reactions to build complex structures. This highlights the challenge and creativity required in developing such intricate molecules.
  • Potential for Drug Development: Given its unique composition, this compound could serve as a valuable framework for the development of new pharmaceuticals. Researchers are continuously searching for novel compounds to treat various ailments, and derivatives of this structure may hold the key.

In conclusion, 2-[3-(4-chlorophenyl)propyl]-6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium; 4-hydroxy-4-oxo-but-2-enoate exemplifies the intricate nature of organic compounds and their potential within the realm of drug discovery and development. As research continues, uncovering the mechanisms of action and optimizing its chemical properties may lead to significant breakthroughs in healthcare.