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Ioxitalamic acid

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Identification
Molecular formula
C11H9I3NO4
CAS number
27237-65-4
IUPAC name
2-(3-acetamido-2,4,6-triiodo-phenoxy)butanoic acid
State
State

At room temperature, ioxitalamic acid is normally found in a solid state.

Melting point (Celsius)
195.00
Melting point (Kelvin)
468.15
Boiling point (Celsius)
420.00
Boiling point (Kelvin)
693.15
General information
Molecular weight
613.97g/mol
Molar mass
613.9660g/mol
Density
2.1185g/cm3
Appearence

Ioxitalamic acid appears as a white crystalline powder. It is not highly soluble in water but is more soluble in certain organic solvents.

Comment on solubility

Solubility of 2-(3-acetamido-2,4,6-triiodo-phenoxy)butanoic acid

The solubility of 2-(3-acetamido-2,4,6-triiodo-phenoxy)butanoic acid is an intriguing topic due to the compound's unique structural features. Understanding its solubility can provide insights into its potential applications and behavior in different environments.

Here are some key points regarding the solubility of this compound:

  • Polar Nature: The presence of the acetamido functional group generally enhances solubility in polar solvents, particularly in water.
  • Iodine Substituents: The multiple iodine atoms attached to the phenolic ring can impact the overall hydrophilicity, potentially reducing solubility in aqueous solutions.
  • Solvent Interactions: The compound is likely to exhibit greater solubility in organic solvents such as dimethyl sulfoxide (DMSO) and ethanol compared to water.
  • pH Dependence: The solubility can vary with pH, as the acidic nature of butanoic acid may lead to the formation of ionic species in alkaline conditions, enhancing solubility.

As noted, "solubility is a key aspect that influences the behavior of chemical compounds in biological and environmental systems." For 2-(3-acetamido-2,4,6-triiodo-phenoxy)butanoic acid, the interplay between its structural components plays a significant role in determining its solubility characteristics.

Interesting facts

Interesting Facts about 2-(3-Acetamido-2,4,6-triiodo-phenoxy)butanoic Acid

2-(3-Acetamido-2,4,6-triiodo-phenoxy)butanoic acid is a unique chemical compound that showcases the intricacies of organic chemistry, particularly in the field of pharmaceuticals and medicinal chemistry. Below are some engaging facts about this compound:

  • Composition and Structure: This compound features a triiodo-substituted aromatic ring, which is quite rare in organic compounds. The presence of three iodine atoms significantly influences the compound's chemical behavior and properties.
  • Pharmacological Potential: Due to its structure, this compound has been investigated for its potential applications in drug development related to thyroid disorders and other hormonal treatments. The iodine substituents can mimic the action of naturally occurring iodinated compounds, making it an interesting subject for research.
  • Scientific Interest: The acetamido group in the molecule can enhance its lipophilicity, which is a critical factor in the design of compounds that need to interact with lipid membranes, such as cell membranes.
  • Environmental Considerations: Compounds containing iodine can have implications in environmental chemistry, especially in bioremediation processes and the tracking of chemical transformations in ecosystems.
  • Analytical Techniques: Researchers employ various analytical techniques, such as NMR and mass spectrometry, to characterize and study the behavior of this compound. These methods help elucidate the compound's structure and confirm its purity.

In summary, 2-(3-acetamido-2,4,6-triiodo-phenoxy)butanoic acid not only highlights the depth of synthetic chemistry but also opens avenues for further investigation in both medicinal and environmental applications. The interplay between its iodine substitutions and the butanoic acid moiety presents intriguing possibilities for innovative research.

Synonyms
BRN 2671852
2-(3-Acetamido-2,4,6-triiodophenoxy)butyric acid
24338-95-2
BUTYRIC ACID, 2-(3-ACETAMIDO-2,4,6-TRIIODOPHENOXY)-
RefChem:331245
DTXSID60947169
2-{3-[(1-Hydroxyethylidene)amino]-2,4,6-triiodophenoxy}butanoic acid