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Iodinated contrast media

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Identification
Molecular formula
C10H8I3NO3
CAS number
132-94-9
IUPAC name
2-(3-acetamido-2,4,6-triiodo-phenyl)acetic acid
State
State

At room temperature, this compound exists as a solid, typically in the form of a powder. Due to its iodine content, it is relatively dense compared to other organic molecules.

Melting point (Celsius)
230.00
Melting point (Kelvin)
503.15
Boiling point (Celsius)
458.00
Boiling point (Kelvin)
731.15
General information
Molecular weight
541.99g/mol
Molar mass
541.9880g/mol
Density
2.3000g/cm3
Appearence

This compound is generally found as a crystalline powder with a white to off-white appearance. The presence of iodine atoms gives it a slightly denser structure compared to non-iodinated organic compounds.

Comment on solubility

Solubility of 2-(3-acetamido-2,4,6-triiodo-phenyl)acetic acid

The solubility of 2-(3-acetamido-2,4,6-triiodo-phenyl)acetic acid can be influenced by several factors due to its complex molecular structure. Here are some key points regarding its solubility:

  • Polarity: The presence of polar functional groups, such as the acetamido group, suggests that this compound may have some degree of solubility in polar solvents like water.
  • Iodine Substituents: The triiodo-substituted phenyl ring might hinder solubility in nonpolar solvents due to the bulky iodine atoms.
  • Hydrogen Bonding: The carboxylic acid (-COOH) group can facilitate hydrogen bonding, further enhancing its solubility characteristics in polar media.
  • Solvent Compatibility: This compound could show differing solubility in various solvents, making solvent selection pivotal in experimental conditions.

In summary, while 2-(3-acetamido-2,4,6-triiodo-phenyl)acetic acid may exhibit reasonable solubility in polar solvents, it may be less soluble in nonpolar environments due to the competing effects of hydrophilic and hydrophobic components. Careful analysis and experimentation are required to characterize its precise solubility profile.

Interesting facts

Interesting Facts about 2-(3-acetamido-2,4,6-triiodo-phenyl)acetic Acid

2-(3-acetamido-2,4,6-triiodo-phenyl)acetic acid, commonly referred to in its abbreviated form, is a fascinating compound noteworthy for its unique combination of iodine substitutions and functional groups. Here are some interesting insights:

  • Structural Complexity: This compound features a phenyl ring that is heavily substituted with three iodine atoms and an acetamido group, which contributes to its intriguing chemical reactivity and properties.
  • Medical Relevance: Compounds with iodine atoms are often studied for their applications in medical imaging, particularly in radiology and nuclear medicine, due to the radioisotopes of iodine used for diagnostics.
  • Potential Anti-Cancer Agent: The molecular structure suggests potential biological activity, making it a promising candidate for research in anti-cancer therapies as compounds with similar structures have shown to interfere with cancer cell proliferation.
  • Halogen Chemistry: The presence of iodine is significant in the realm of halogen chemistry, as halogens often enhance reactivity and influence the biological behavior of organic compounds.
  • Synthesis Journey: The synthesis of such derivatives often involves multi-step reactions, making it a challenging yet rewarding endeavor for chemistry students and researchers looking to expand their expertise in organic synthesis.

Moreover, its role in various chemical assays and potential to serve as a lead compound for further drug development exemplifies the incredible journey that compounds like 2-(3-acetamido-2,4,6-triiodo-phenyl)acetic acid can undergo in the realms of both academic research and industrial applications.

Synonyms
BRN 2753527
ACETIC ACID, (3-ACETAMIDO-2,4,6-TRIIODOPHENYL)-
(3-Acetamido-2,4,6-triiodophenyl)acetic acid
Acido 3-acetilamino-2,4,6-triiodofenilacetico [Italian]
3119-16-2
Acido 3-acetilamino-2,4,6-triiodofenilacetico
DTXSID20185121
DTXCID30107612