Skip to main content

Iopanoic acid

ADVERTISEMENT
Identification
Molecular formula
C11H12I3NO3
CAS number
96-83-3
IUPAC name
2-(3-acetamido-2,4,6-triiodo-phenyl)butanoic acid
State
State

At room temperature, Iopanoic acid exists in a solid state. It is commonly provided in a crystalline form for various applications.

Melting point (Celsius)
223.00
Melting point (Kelvin)
496.15
Boiling point (Celsius)
330.00
Boiling point (Kelvin)
603.15
General information
Molecular weight
597.94g/mol
Molar mass
597.9430g/mol
Density
2.3300g/cm3
Appearence

Iopanoic acid typically appears as a white to off-white crystalline powder. It is odorless and its crystalline nature is standard for many organic acids, particularly those used in medicinal applications.

Comment on solubility

Solubility of 2-(3-acetamido-2,4,6-triiodo-phenyl)butanoic acid

The solubility of 2-(3-acetamido-2,4,6-triiodo-phenyl)butanoic acid is influenced by several factors due to its unique molecular structure. This compound, with its complex aromatic ring and iodine substitutions, presents interesting characteristics when considering its behavior in various solvents.

Key observations regarding its solubility include:

  • Polarity: The presence of the acetamido group introduces some polarity to the compound, enhancing its solubility in polar solvents, such as water and alcohols, though the triiodo substitutions may counterbalance this effect.
  • Hydrogen Bonding: The amide functionality can engage in hydrogen bonding, which can contribute to improved solubility in certain solvents, especially when compared to similar compounds lacking such groups.
  • Hydrophobic Interactions: The triiodo substitutions increase the hydrophobic character of the molecule, potentially reducing its overall solubility in strictly aqueous environments.

In summary, while 2-(3-acetamido-2,4,6-triiodo-phenyl)butanoic acid might exhibit moderate solubility in polar solvents due to hydrogen bonding and its polar amide group, the influence of its hydrophobic triiodo moieties can lead to more complex solubility behaviors in mixed solvents. Understanding the balance between these factors is crucial for predicting its solubility in various applications.

Interesting facts

Interesting Facts about 2-(3-acetamido-2,4,6-triiodo-phenyl)butanoic Acid

2-(3-acetamido-2,4,6-triiodo-phenyl)butanoic acid is a fascinating compound with applications that span various scientific domains. Here are some intriguing insights about this particular structure:

  • Medical Significance: The introduction of iodine atoms in its structure allows for potential usage in imaging modalities like Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT), making it a candidate for tumor targeting and diagnosis.
  • Therapeutic Potential: Its acetamido group contributes to enhanced solubility and biological activity, which can drive investigations into anti-inflammatory or anticancer properties.
  • Synthetic Challenges: The multi-step synthesis of this compound often requires careful control of reaction conditions to prevent unwanted side reactions, particularly due to the reactivity of the iodine substituents.
  • Structure-Activity Relationship: The unique arrangement of functional groups around the butanoic acid backbone aids in studying how changes in molecular structure can impact biological activity.
  • Chemical Stability: Iodine-containing compounds can exhibit fascinating behavior under different conditions; understanding their stability can lead to better application and utilization in pharmaceuticals.

As a compound with such a complex and multifaceted structure, 2-(3-acetamido-2,4,6-triiodo-phenyl)butanoic acid stands as a prime example of how chemical innovation can impact health sciences and provide pivotal insights into molecular pharmacology. Continual research exploring its properties and potential applications underscores the ever-evolving nature of chemistry.

Synonyms
BRN 3037425
23279-53-0
2-(3-Acetamido-2,4,6-triiodophenyl)butyric acid
BUTYRIC ACID, 2-(3-ACETAMIDO-2,4,6-TRIIODOPHENYL)-
RefChem:331246
DTXSID40945966
2-{3-[(1-Hydroxyethylidene)amino]-2,4,6-triiodophenyl}butanoic acid