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Acetylsalicylic acid

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Identification
Molecular formula
C9H8O4
CAS number
50-78-2
IUPAC name
2-[3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxybenzoic acid
State
State

At room temperature, acetylsalicylic acid is in a solid state. It remains stable as a crystalline powder, primarily used in formulating medications such as aspirin.

Melting point (Celsius)
136.00
Melting point (Kelvin)
409.15
Boiling point (Celsius)
140.00
Boiling point (Kelvin)
413.15
General information
Molecular weight
180.16g/mol
Molar mass
180.1570g/mol
Density
1.3500g/cm3
Appearence

Acetylsalicylic acid appears as a white, crystalline solid. It is commonly found in powder or tablet form when used in pharmaceutical applications. This compound is both odorless and stable under normal conditions.

Comment on solubility

Solubility of 2-[3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxybenzoic acid (C9H8O4)

The solubility of 2-[3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxybenzoic acid is influenced by its complex structure, which contains several functional groups that can interact with polar solvents.

Key Factors Affecting Solubility:

  • Polarity: The presence of hydroxyl (-OH) groups contributes to strong hydrogen bonding capabilities, enhancing solubility in polar solvents like water.
  • Acidic Nature: Being a benzoic acid derivative, it displays acidic properties which may increase solubility in alkaline conditions due to ionization.
  • Hydrophilic Moieties: The acetamido and hydroxymethyl groups add to the hydrophilicity, making it more soluble in aqueous solutions.

In general, compounds like this one tend to be more soluble in polar solvents and less soluble in non-polar solvents. As a rule of thumb, "like dissolves like," meaning that the solubility profile is significantly affected by the nature of the solvent employed.

Solubility Insights:

When considering solubility in practice, keep these points in mind:

  • Always check for pH dependence—the solubility can vary in acidic versus basic solutions.
  • Consult solubility tables for specific conditions if available, as experimental data may provide the most accurate insights.

In conclusion, the solubility of 2-[3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxybenzoic acid is expected to be quite favorable in polar solvents due to its structural characteristics.

Interesting facts

Interesting Facts about 2-[3-Acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxybenzoic Acid

This intriguing compound is a derivative of benzoic acid, featuring unique structural characteristics that enhance its functionality in various applications. Here are some key points to consider:

  • Biological Importance: The presence of the acetamido and hydroxymethyl groups suggests a potential role in biological systems, possibly influencing metabolic pathways or acting as a biochemical marker.
  • Structural Complexity: With a tetrahydropyran ring and multiple hydroxyl groups, this compound exhibits significant stereochemical diversity, which may affect its chemical reactivity and interaction with other molecules.
  • Potential Applications: Due to its functional groups, this compound may find applications in pharmaceuticals, particularly as a precursor for drug synthesis or as a targeted compound for specific therapeutic actions.
  • Synthetic Pathways: Understanding the synthesis of this compound can provide insight into multi-step organic transformations. It challenges chemists to consider various methods of constructing complex molecules from simpler precursors.
  • Research Frontiers: Investigating 2-[3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxybenzoic acid may open up new avenues for research in fields such as medicinal chemistry, biochemistry, and material science, highlighting its versatility and potential as a bioactive agent.

Overall, the intricate nature of this compound underscores the beauty of organic chemistry, where the implications of structural variations can lead to profound scientific discoveries.

Synonyms
2-(3-Acetylamino-4,5-dihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-benzoic acid