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Tilorone

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Identification
Molecular formula
C25H35ClN2O3
CAS number
27591-97-5
IUPAC name
2-[3-acetyl-2-methyl-1-(p-tolyl)indol-5-yl]oxyethyl-diethyl-ammonium;chloride
State
State

At room temperature, tilorone is typically found as a solid. It is often handled in the form of a hydrochloride salt, which affects its solubility profile for pharmaceutical applications.

Melting point (Celsius)
197.00
Melting point (Kelvin)
470.15
Boiling point (Celsius)
473.80
Boiling point (Kelvin)
746.95
General information
Molecular weight
411.01g/mol
Molar mass
411.0060g/mol
Density
1.1643g/cm3
Appearence

Tilorone usually appears as a fine crystalline solid. It is typically available in its hydrochloride salt form for enhanced solubility and stability.

Comment on solubility

Solubility of 2-[3-acetyl-2-methyl-1-(p-tolyl)indol-5-yl]oxyethyl-diethyl-ammonium;chloride

The solubility of 2-[3-acetyl-2-methyl-1-(p-tolyl)indol-5-yl]oxyethyl-diethyl-ammonium;chloride is an intriguing aspect to consider, particularly due to its unique structural components.

In general, the solubility of compounds can be influenced by several factors including:

  • Polarity: The presence of both hydrophilic (polar) and hydrophobic (non-polar) regions in the molecule can greatly affect its solubility in various solvents.
  • Ionic Nature: Being a salt (as indicated by the presence of chloride), the ionic character may enhance solubility in water, due to the solvent's ability to stabilize charged ions.
  • Temperature: Solubility often increases with temperature, which is important to consider in practical applications.
  • pH Level: As a quaternary ammonium compound, its solubility may be pH-dependent, with alterations in protonation state potentially impacting its interaction with solvents.

In many cases, it can be anticipated that quaternary ammonium salts are readily soluble in polar solvents like water, while demonstrating limited solubility in non-polar solvents. This information is crucial for understanding the compound's behavior in biological systems or during synthesis processes.

Overall, clarifying the solubility of this compound not only helps in predicting its practical applications but can also guide further research into its potential uses." In summary, while specific empirical data would provide greater insight, the initial expectations of solubility by structural analysis yield a fascinating landscape for exploration.

Interesting facts

Interesting Facts about 2-[3-acetyl-2-methyl-1-(p-tolyl)indol-5-yl]oxyethyl-diethyl-ammonium;chloride

This unique compound, known scientifically as 2-[3-acetyl-2-methyl-1-(p-tolyl)indol-5-yl]oxyethyl-diethyl-ammonium;chloride, plays an intriguing role in the field of synthetic organic chemistry. Here are some notable aspects:

  • Structural Complexity: The compound features an indole moiety, which is integral to numerous biologically active compounds. Indoles are known for their diverse chemical behavior due to the presence of a nitrogen atom in the aromatic system.
  • Acetyl and Methyl Substituents: The presence of both acetyl and methyl groups may enhance the compound's lipophilicity, potentially affecting its ability to interact with biological membranes.
  • Ammonium Salt Formation: As a quaternary ammonium compound, it exhibits characteristics typical of ionic compounds, including enhanced solubility in polar solvents and potential surfactant properties.
  • Biological Implications: Compounds with similar structures are often explored for their potential therapeutic effects. This could include antimicrobial, anticancer, or anti-inflammatory properties due to the indole structure.
  • Versatility in Research: The compound's structural features make it a subject of interest in various research fields, including medicinal chemistry and pharmacology. Chemists might investigate its effectiveness as a reagent or possible drug.

Moreover, as a student or scientist in chemistry, you might find it fascinating to explore how modifications in the structure can lead to significant changes in functionality and efficacy. The compound exemplifies the ingenuity of chemical synthesis and the importance of understanding structure-activity relationships in drug development.

In conclusion, this compound is a striking example of how structural diversity in chemistry can lead to novel applications and discoveries.

Synonyms
Of-2440
Ketone, 5-(2-(diethylamino)ethoxy)-2-methyl-1-p-tolylindol-3-yl methyl, monohydrochloride
OF 2440
18235-92-2
5-(2-(Diethylamino)ethoxy)-2-methyl-1-p-tolylindol-3-yl methyl ketone monohydrochloride