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Iopanoic acid

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Identification
Molecular formula
C11H12I3NO3
CAS number
96-83-3
IUPAC name
2-[3-[acetyl(benzyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid
State
State

Iopanoic acid is in a solid state at room temperature.

Melting point (Celsius)
235.00
Melting point (Kelvin)
508.15
Boiling point (Celsius)
740.00
Boiling point (Kelvin)
1 013.15
General information
Molecular weight
597.95g/mol
Molar mass
597.9470g/mol
Density
3.2800g/cm3
Appearence

Iopanoic acid appears as a white crystalline powder. It is odorless and is typically used in the form of its sodium salt for its solubility in water, facilitating its use in certain medical applications.

Comment on solubility

Solubility of 2-[3-[acetyl(benzyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid

The solubility of 2-[3-[acetyl(benzyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid presents a fascinating study due to its unique structural components and iodine substituents. This compound exhibits characteristics that can be grouped into key solubility influencing factors:

  • Polarity: The presence of polar functional groups, such as the carboxylic acid and amine functionalities, typically increases solubility in polar solvents, particularly water.
  • Hydrophobic interactions: However, the long hexanoic acid chain and the benzyl group introduce significant hydrophobic characteristics, which may diminish overall solubility in polar environments.
  • Iodine's influence: The triiodo substitution could further complicate solubility. Iodine is relatively large and has a low electronegativity, potentially reducing interactions with polar solvents.

As a result, it is reasonable to anticipate that 2-[3-[acetyl(benzyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid may exhibit limited solubility in water but could be more soluble in organic solvents such as ethanol or acetone. This duality in solubility makes it a prime candidate for applications requiring selective solubility profiles.

In summary, predicting the solubility of this intriguing compound demands an assessment of both its polar and nonpolar characteristics, leading to a nuanced understanding of its behavior in various solvents.

Interesting facts

Interesting Facts about 2-[3-[Acetyl(benzyl)amino]-2,4,6-triiodo-phenoxy]hexanoic Acid

This fascinating compound presents a unique blend of structure and activity, making it a subject of interest in various fields of chemical research. Here are some captivating insights:

  • Complex Structure: The molecule features a tri-iodinated phenoxy group, which is significant for its potential biological activity. Iodine substitution can enhance the lipophilicity of molecules and influence their interactions in biological systems.
  • Biological Relevance: Compounds like this one are often explored for their pharmacological properties. The presence of the acetyl(benzyl)amino group suggests potential interactions with biological targets, making it relevant for medicinal chemistry.
  • Synthesis Challenges: Given its complex structure, the synthesis of this compound may involve multiple synthetic steps and the careful handling of reagents, particularly those containing iodine.
  • Environmental Considerations: Iodinated compounds can be used in various applications ranging from pharmaceuticals to imaging agents. However, the environmental impact and bioaccumulation of iodine are important factors to consider during its use and disposal.
  • Research Potential: Due to its intricate design, this compound could provide pathways for research in drug development, particularly in designing new treatments that target specific biological pathways.

In summary, 2-[3-[acetyl(benzyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid exemplifies the convergence of chemistry and biology, paving the way for innovative advancements in medicinal applications and therapeutic agents.

Synonyms
BRN 2683024
22275-41-8
2-(3-(N-Benzylacetamido)-2,4,6-triiodophenoxy)hexanoic acid
HEXANOIC ACID, 2-(3-(N-BENZYLACETAMIDO)-2,4,6-TRIIODOPHENOXY)-
RefChem:347658
DTXSID60944936
2-{3-[Acetyl(benzyl)amino]-2,4,6-triiodophenoxy}hexanoic acid