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Iodixanol

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Identification
Molecular formula
C32H44I6N6O12
CAS number
92339-11-2
IUPAC name
2-[3-[acetyl(benzyl)amino]-2,4,6-triiodo-phenyl]acetic acid
State
State

At room temperature, iodixanol is typically a solid.

Melting point (Celsius)
154.00
Melting point (Kelvin)
427.15
Boiling point (Celsius)
213.00
Boiling point (Kelvin)
486.15
General information
Molecular weight
789.12g/mol
Molar mass
1 501.2200g/mol
Density
2.0490g/cm3
Appearence

Iodixanol appears as a white to off-white crystalline powder. It is nearly odorless and hygroscopic in nature.

Comment on solubility

Solubility of 2-[3-[acetyl(benzyl)amino]-2,4,6-triiodo-phenyl]acetic acid

The solubility of 2-[3-[acetyl(benzyl)amino]-2,4,6-triiodo-phenyl]acetic acid can be influenced by several factors, including temperature, pH, and the presence of solvents. Here are some key points to consider:

  • Polarity: The presence of multiple polar functional groups, such as amino and carboxylic acid, suggests that this compound could exhibit good solubility in polar solvents like water.
  • Hydrophobic regions: The acetyl(benzyl) moiety and the triiodophenyl group may introduce hydrophobic characteristics, potentially reducing overall solubility in highly polar solvents.
  • Solvent interactions: This compound is likely to solubilize effectively in organic solvents such as ethanol and methanol, where both polar and nonpolar interactions can play a role.
  • Temperature Sensitivity: As is often the case with organic compounds, increasing the temperature might enhance its solubility, promoting greater molecular interactions.

In summary, while the presence of polar functional groups may facilitate solubility, the hydrophobic characteristics can complicate it. It is crucial to consider the medium when studying the solubility behavior of this compound, as it may vary significantly based on the solvent environment.

Interesting facts

Interesting Facts About 2-[3-[acetyl(benzyl)amino]-2,4,6-triiodo-phenyl]acetic acid

This compound is a fascinating member of the aryl acetic acid family, distinguished by its numerous iodine atoms which imbue it with unique chemical properties. Its complexity and structural intricacies open up a world of interesting discussions:

  • Pharmacological Relevance: Compounds containing iodine are often explored in medicinal chemistry due to their roles in enhancing biological activity. The presence of iodine in this compound may potentially contribute to its effectiveness in various pharmaceutical applications.
  • Structural Diversity: The combination of an acetyl group with a benzylamine framework alongside the triiodo-phenyl moiety illustrates significant structural diversity. Such structural attributes are key in the development of targeted therapeutic agents.
  • Reactivity and Stability: The presence of multiple iodine substituents affects both the reactivity and stability of the compound. Iodinated compounds often have altered reactivity due to the electron-withdrawing nature of iodine.
  • Potential Applications: Beyond pharmaceuticals, this compound may hold promise in areas like dye synthesis due to its rich aromatic character and ability to undergo various chemical transformations.

Moreover, the exploration of this compound can lead to advancements in understanding how halogenated compounds function biologically, particularly regarding their mechanism of action and interaction with biological targets. As a scientist or chemistry student, the study of such compounds is both challenging and rewarding, serving as a reminder of the intricate web of relationships existing within chemistry.

Synonyms
BRN 3013576
29193-35-9
ACETIC ACID, (3-(N-BENZYLACETAMIDO)-2,4,6-TRIIODOPHENYL)-
(3-(N-Benzylacetamido)-2,4,6-triiodophenyl)acetic acid
DTXSID60183449
RefChem:316181
DTXCID20105940