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Iopanoic acid

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Identification
Molecular formula
C11H12I3NO3
CAS number
96-83-3
IUPAC name
2-[3-[acetyl(butyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid
State
State

At room temperature, iopanoic acid exists as a solid. It is stable under normal conditions and does not readily react with other substances in its solid state.

Melting point (Celsius)
433.00
Melting point (Kelvin)
706.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
597.94g/mol
Molar mass
597.9390g/mol
Density
3.2800g/cm3
Appearence

Iopanoic acid appears as a white crystalline powder. It is typically odorless and has a slightly bitter taste. It is often used in its solid form for further formulation in pharmaceuticals.

Comment on solubility

Solubility of 2-[3-[acetyl(butyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid

This compound, known as 2-[3-[acetyl(butyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid, exhibits intriguing solubility characteristics that are influenced by its complex structure. Understanding its solubility can provide insights into its behavior in various chemical environments. Here are some key points regarding its solubility:

  • Polarity: The presence of multiple functional groups, including an amine and a phenoxy structure, enhances the polarity of the compound.
  • Hydrophobic vs. Hydrophilic: While the butyl group adds a hydrophobic character, the presence of the carboxylic acid group contributes to a degree of hydrophilicity.
  • Solubility in Solvents: This duality in polarity suggests that the compound may be soluble in:
    • Hydrophobic solvents (e.g., organic solvents like chloroform and ethanol)
    • Conditional solubility in polar solvents (depending on pH and ionic strength)
  • Temperature Effects: As with many organic compounds, solubility may be enhanced with an increase in temperature.
  • pH Influence: The acidity of the solution can significantly influence solubility; a lower pH may protonate functional groups, increasing polarity and promoting solubility in aqueous solutions.

In summary, the solubility of 2-[3-[acetyl(butyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid is a result of a delicate balance between its polar and non-polar characteristics, with multiple factors affecting its behavior in different solvents.

Interesting facts

Interesting Facts about 2-[3-[acetyl(butyl)amino]-2,4,6-triiodo-phenoxy]hexanoic Acid

2-[3-[acetyl(butyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid is a fascinating compound with several noteworthy features that underscore its importance in the realm of chemistry.

1. Biological Significance

This compound is of particular interest in biochemical research due to its potential applications in drug development. The presence of iodine atoms within its structure can impart unique biological properties, making it a candidate for use in various therapeutic agents.

2. Influence of Iodine

  • Iodinated Compounds: The incorporation of iodine makes this compound stand out as it can improve the solubility and stability of pharmaceuticals.
  • Radioactive Applications: Iodine is often utilized in medical imaging and radiotherapy, providing valuable diagnostic capabilities.

3. Structure-Activity Relationships (SAR)

The structure of this compound creates a complex interaction between its functional groups, allowing chemists to explore how modifications can enhance its activity. Understanding SAR is crucial for developing more effective drugs:

  • Acetyl Group: This functional group may facilitate penetration through biological membranes, enhancing bioavailability.
  • Butyl Chain: The hydrophobic nature of the butyl group can also influence the compound’s interaction with lipid membranes.

4. Synthesis Challenges

As with many complex organic compounds, synthesizing this acid involves intricate reaction pathways. Chemists often face challenges such as:

  • Reagent Selection: Choosing appropriate reagents to achieve selective iodination of the aromatic ring.
  • Yield Optimization: Maximizing the yield and purity of the final product requires careful planning and execution of reaction conditions.

5. Future Research Directions

The ongoing exploration of compounds like 2-[3-[acetyl(butyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid highlights the vibrancy of chemical research. Scientists are investigating:

  • The compound’s mechanism of action in biological systems.
  • Its potential for development into new diagnostic tools or therapeutic agents.

In conclusion, 2-[3-[acetyl(butyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid is a compound rich in potential and significance, playing a crucial role in the intersections of chemistry, biology, and medicine.

Synonyms
BRN 2710787
24340-22-5
2-(3-(N-Butylacetamido)-2,4,6-triiodophenoxy)hexanoic acid
HEXANOIC ACID, 2-(3-(N-BUTYLACETAMIDO)-2,4,6-TRIIODOPHENOXY)-
RefChem:347659
DTXSID20947180
2-{3-[Acetyl(butyl)amino]-2,4,6-triiodophenoxy}hexanoic acid