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Iodoxamic acid

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Identification
Molecular formula
C13H16I3NO4
CAS number
31130-52-0
IUPAC name
2-[3-[acetyl(butyl)amino]-2,4,6-triiodo-phenyl]acetic acid
State
State

At room temperature, Iodoxamic acid is typically in a solid state with a crystalline structure. It is stable under normal conditions but should be stored in a dry environment to prevent degradation.

Melting point (Celsius)
238.00
Melting point (Kelvin)
511.00
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.00
General information
Molecular weight
613.98g/mol
Molar mass
613.9840g/mol
Density
3.2600g/cm3
Appearence

Iodoxamic acid is a white to off-white crystalline powder. It may appear slightly less white due to impurities or handling, but its fundamental nature is as a crystalline solid.

Comment on solubility

Solubility of 2-[3-[acetyl(butyl)amino]-2,4,6-triiodo-phenyl]acetic acid

The solubility of a compound can be influenced by various structural and chemical properties. For 2-[3-[acetyl(butyl)amino]-2,4,6-triiodo-phenyl]acetic acid, several key factors play a crucial role:

  • Polarity: The presence of functional groups such as the acetyl and amino moieties contributes to the polarity of the compound, which often enhances solubility in polar solvents.
  • Iodine Substitution: The extensive iodination on the phenyl ring increases the molecular weight and may reduce aqueous solubility due to steric hindrance and lower interaction with water molecules.
  • Acidic Nature: As a carboxylic acid, it can form salts in the presence of bases, potentially increasing solubility in alkaline solutions.
  • Solvent Interaction: This compound may exhibit variable solubility in organic solvents such as DMSO or ethanol, depending on the solvent's ability to stabilize the different functional groups.

In conclusion, while the overall solubility of 2-[3-[acetyl(butyl)amino]-2,4,6-triiodo-phenyl]acetic acid is likely to be limited in water due to its heavy halogen substitution and increased molecular complexity, it may demonstrate enhanced solubility in suitable organic solvents. Understanding the specific interactions with solvents is crucial for effectively utilizing this compound in various chemical applications.

Interesting facts

Interesting Facts about 2-[3-[Acetyl(butyl)amino]-2,4,6-triiodo-phenyl]acetic Acid

2-[3-[Acetyl(butyl)amino]-2,4,6-triiodo-phenyl]acetic acid is a fascinating chemical compound that highlights the intersection of chemistry and pharmacology. Here are some intriguing insights regarding this compound:

  • Iodinated Aromatic Compound: This compound features a striking structure that includes three iodine atoms attached to a phenyl ring. Iodine is known for its ability to enhance the compound's biological activity and imaging properties, making it prominent in various medicinal applications.
  • Biological Relevance: Compounds like this are often researched for their potential in drug development. The acetyl(butyl)amino group suggests that it may interact favorably with biological targets, possibly serving as a starting point for synthesizing new therapeutic agents.
  • Synthesis and Modification: The presence of both acetyl and butyl groups opens up pathways for further chemical modification. Scientists can utilize this compound as a scaffold for synthesizing related compounds, exploring variations to improve efficacy and reduce side effects.
  • Analytical Challenges: Due to the presence of multiple halogens and the complexity of the molecule, analytical chemists encounter unique challenges when it comes to identifying and quantifying this compound in mixtures. Techniques such as NMR and mass spectrometry are crucial in accurately characterizing it.

As a potential player in the pharmaceutical arena, 2-[3-[Acetyl(butyl)amino]-2,4,6-triiodo-phenyl]acetic acid serves as an excellent example of how chemical compounds can embody the intricate relationship between structure and function in biochemistry. By understanding its properties and synthesis, researchers can unlock new possibilities in therapeutic development.

Synonyms
BRN 3006754
29193-36-0
ACETIC ACID, (3-(N-BUTYLACETAMIDO)-2,4,6-TRIIODOPHENYL)-
(3-(N-Butylacetamido)-2,4,6-triiodophenyl)acetic acid
DTXSID70183450
RefChem:316184
DTXCID80105941