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Ioxitalamic acid

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Identification
Molecular formula
C13H12I4N1O4
CAS number
51084-83-0
IUPAC name
2-[3-[acetyl(ethyl)amino]-2,4,6-triiodo-phenoxy]-2-(4-iodophenyl)acetic acid
State
State

At room temperature, ioxitalamic acid is a solid.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
791.97g/mol
Molar mass
791.9740g/mol
Density
2.3000g/cm3
Appearence

Ioxitalamic acid is typically a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-[3-[acetyl(ethyl)amino]-2,4,6-triiodo-phenoxy]-2-(4-iodophenyl)acetic acid

The solubility of 2-[3-[acetyl(ethyl)amino]-2,4,6-triiodo-phenoxy]-2-(4-iodophenyl)acetic acid is influenced by several key factors:

  • Polarity: The presence of multiple iodine atoms suggests that this compound has significant polarity, which can affect its interaction with solvents. Iodine, being a large atom, can impact the molecular structure and thus the solubility.
  • Functional Groups: The acetyl and amino functional groups can enhance solubility in polar solvents. Specifically:
    • The acetyl group renders it partially hydrophilic.
    • The ethyl amino group may increase solubility in both polar and non-polar environments depending on the medium.
  • Hydrogen Bonding: The ability of the compound to engage in hydrogen bonding with solvents can further affect its solubility. This is significant in systems where the compound interfaces with water or alcohols.

In general, one could expect that:

  1. The compound may show higher solubility in polar solvents like water, particularly at elevated temperatures.
  2. It might have lower solubility in non-polar solvents due to the bulky iodine substituents, which can hinder interaction with less polar solvents.

Ultimately, experimentation would be required to accurately determine the solubility profile, as theoretical predictions may not always align with practical outcomes, especially for complex compounds such as this.

Interesting facts

Interesting Facts about 2-[3-[acetyl(ethyl)amino]-2,4,6-triiodo-phenoxy]-2-(4-iodophenyl)acetic acid

This intriguing compound showcases the complexity and diversity of organoiodine chemistry. With multiple iodine atoms present, this compound belongs to a class of molecules known for their unique properties and various applications.

Key Features:

  • Organoiodine Background: Organoiodine compounds are known for their utility in pharmaceuticals, particularly in the development of radioiodinated drugs for imaging and therapeutic uses.
  • Molecular Composition: The presence of the acetyl(ethyl)amino group introduces both steric and electronic factors that can enhance biological activity.
  • Structural Diversity: This compound's structure allows for various interactions, making it particularly interesting for researchers exploring new medicinal compounds.

As chemists explore the applications of this compound, they are often struck by the *biological implications* of combining iodine with organic functional groups. The iodine atoms not only influence the compound's reactivity but are also **crucial in imaging** techniques in medicine.

Potential Applications:

  • Development of **antioxidants** and **anti-inflammatory agents**.
  • Utilization in **targeted drug delivery systems**, leveraging the iodine's properties for imaging.
  • Research into **radiopharmaceuticals** for diagnosis and treatment in cancer therapy.

This compound serves as a reminder of the exciting possibilities that arise from the intersection of organometallic chemistry and biochemistry. As research continues, it is fascinating to ponder the potential breakthroughs that may emerge from the study of such richly functionalized compounds.

Synonyms
BRN 2919140
23280-17-3
2-(3-(N-Ethylacetamino)-2,4,6-triiodophenoxy)-2-(p-iodophenyl)acetic acid
Acido (4-iodofenil)(3-N-etilacetilamino-2,4,6-triiodofenossi)acetico [Italian]
Benzeneacetic acid, alpha-(3-(acetylethylamino)-2,4,6-triiodophenoxy)-4-iodo-
ACETIC ACID, 2-(3-(N-ETHYLACETAMIDO)-2,4,6-TRIIODOPHENOXY)-2-(p-IODOPHENYL)-
Acido (4-iodofenil)(3-N-etilacetilamino-2,4,6-triiodofenossi)acetico
RefChem:316438
Benzeneacetic acid, alpha-(3-(acetylethylamino)-2,4,6-triiodophenoxy)-4-iodo-(9CI)
DTXSID90945971
{3-[acetyl(ethyl)amino]-2,4,6-triiodophenoxy}(4-iodophenyl)acetic acid