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Iodipamide

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Identification
Molecular formula
C20H13I3N2O6
CAS number
18810-58-5
IUPAC name
2-[3-[acetyl(ethyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid
State
State

At room temperature, iodipamide is typically in a solid state and is generally handled as a powder or crystalline substance.

Melting point (Celsius)
222.00
Melting point (Kelvin)
495.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
889.07g/mol
Molar mass
889.0730g/mol
Density
1.8400g/cm3
Appearence

Iodipamide typically appears as a white or off-white crystalline powder. It is often odorless and has a bitter taste. In solid form, it is quite stable under standard conditions.

Comment on solubility

Solubility of 2-[3-[acetyl(ethyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid

The solubility of 2-[3-[acetyl(ethyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid can be assessed through several key factors that influence its behavior in various solvents. Understanding these factors is essential for practical applications, such as drug formulation and environmental chemistry.

Factors Affecting Solubility:

  • Molecular Structure: The presence of both polar and nonpolar groups in this compound significantly influences solubility. The elongated hexanoic acid chain contributes to its hydrophobic characteristics, while the triiodophenoxy and acetyl(ethyl)amino groups introduce some polarity.
  • pH Sensitivity: This compound may exhibit pH-dependent solubility behavior, where its ionized form could enhance solubility in aqueous solutions.
  • Solvent Nature: The solubility is expected to vary with the solvent polarity; it might be more soluble in polar solvents like dimethyl sulfoxide (DMSO) compared to non-polar solvents.

It is often stated that "like dissolves like," which implies that the solubility can be optimized by selecting appropriate solvents based on the compound's polar and nonpolar features. Testing solubility under various conditions would provide a comprehensive understanding of its behavior in real-world applications.

Interesting facts

Interesting Facts about 2-[3-[acetyl(ethyl)amino]-2,4,6-triiodo-phenoxy]hexanoic Acid

This compound is a fascinating example of a highly substituted organic molecule, featuring a blend of functional groups that provide unique properties and potential applications. Here are some interesting facts:

  • Structure and Substituents: The molecule includes a hexanoic acid backbone, which is key to its biological activity. Its structure features a phenoxy group that is heavily substituted with three iodine atoms, making it highly lipophilic.
  • Potential in Medical Chemistry: The incorporation of iodine makes it a compound of interest in medicinal chemistry, particularly in the development of radiographic imaging agents and antimicrobial agents.
  • Acetyl(ethyl)amino Group: This functional group contributes to the solubility of the compound in biological environments, potentially enhancing its effectiveness as a drug.
  • Research Interest: Researchers are actively exploring the pharmacological applications of triiodo-phenoxy compounds, considering their potential in targeting specific biological pathways due to their unique structure.
  • Environmental Considerations: Compounds with heavy halogen substitutions, like iodine, are also being evaluated for their environmental persistence and effects on ecotoxicology.

In summary, 2-[3-[acetyl(ethyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid represents a complex interplay of organic chemistry and pharmacology, showcasing how tailored structural modifications can lead to novel bioactive compounds.

Synonyms
BRN 2677815
24340-20-3
2-(3-(N-Ethylacetamido)-2,4,6-triiodophenoxy)hexanoic acid
HEXANOIC ACID, 2-(3-(N-ETHYLACETAMIDO)-2,4,6-TRIIODOPHENOXY)-
RefChem:347660
DTXSID50947178
2-{3-[acetyl(ethyl)amino]-2,4,6-triiodophenoxy}hexanoic acid