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Iopromide

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Identification
Molecular formula
C18H24I3N3O8
CAS number
73334-07-3
IUPAC name
2-[3-[acetyl(ethyl)amino]-2,4,6-triiodo-phenyl]butanoic acid
State
State

At room temperature, Iopromide is typically encountered as a stable solid. However, for its primary application in imaging, it is provided as a liquid solution form.

Melting point (Celsius)
183.00
Melting point (Kelvin)
456.15
Boiling point (Celsius)
792.90
Boiling point (Kelvin)
1 066.05
General information
Molecular weight
791.11g/mol
Molar mass
791.1210g/mol
Density
1.4450g/cm3
Appearence

Iopromide appears as a white to off-white powder. As a compound used in pharmaceuticals, particularly as a contrast agent in medical imaging, it is commonly found in solution form for easy administration.

Comment on solubility

Solubility of 2-[3-[acetyl(ethyl)amino]-2,4,6-triiodo-phenyl]butanoic acid

The solubility of 2-[3-[acetyl(ethyl)amino]-2,4,6-triiodo-phenyl]butanoic acid can be influenced by a variety of factors, primarily due to its complex structure and functional groups. Here are some key points to consider regarding its solubility:

  • Polarity: The presence of polar functional groups, such as the carboxylic acid and the amine, suggests that this compound may exhibit a degree of hydrophilicity. This could enhance its solubility in polar solvents like water.
  • Iodine Substitution: The tri-iodo substitution might impart some hydrophobic character, which can complicate solubility in aqueous solutions.
  • Solvent Compatibility: This compound might show better solubility in solvents like dimethyl sulfoxide (DMSO) or ethanol, which can solvate both the polar and non-polar regions effectively.
  • Temperature Dependence: The solubility may vary with temperature; often, increasing temperature can enhance the solubility of organic compounds.

In conclusion, understanding the solubility profile of this compound requires a balanced consideration of its polar and non-polar characteristics, as well as the solvent environment. As always, empirical data should guide specific solubility assessments, but based on its structural features, a moderate level of solubility in organic solvents is anticipated.

Interesting facts

Interesting Facts about 2-[3-[acetyl(ethyl)amino]-2,4,6-triiodo-phenyl]butanoic acid

This fascinating compound, known for its intricate structure and versatile applications, has piqued the interest of chemists and researchers alike. Here are some captivating insights into its properties and potential uses:

  • Pharmaceutical Relevance: The presence of the acetyl(ethyl)amino group indicates potential pharmacological activity. Compounds like this are often examined for their ability to serve as drug candidates, particularly in the realm of anti-inflammatory or analgesic therapies.
  • Triiodophenyl Moiety: The triiodophenyl structure not only gives this compound its name but also contributes to its reactivity and interaction with biological systems. Iodine is known for its role in thyroid hormone synthesis, and compounds with iodine can often exhibit unique biological behavior, thus making them suitable for studies in biochemistry.
  • Analytical Applications: The unique structure allows this compound to be used in various analytical techniques, such as spectroscopy. Its distinct absorption characteristics can be valuable for researchers looking to identify and quantify similar compounds.
  • Research Flexibility: Scientists are continuously exploring the chemistry surrounding such compounds, particularly to understand their mechanisms and effects. Their flexibility in modification allows for the creation of derivatives that could lead to discovering new therapeutic agents.

In summary, 2-[3-[acetyl(ethyl)amino]-2,4,6-triiodo-phenyl]butanoic acid is not just a fascinating compound due to its chemical structure but also because of the exciting avenues of research it opens in medicinal chemistry, analytical methods, and potential pharmaceutical applications. As explored in literature, the synthesis and study of such compounds often lead to significant advancements in chemistry and pharmacology, underscoring the compound's importance in the scientific community.

Synonyms
BRN 3038217
23279-54-1
2-(3-(N-Ethylacetamido)-2,4,6-triiodophenyl)butyric acid
BUTYRIC ACID, 2-(3-(N-ETHYLACETAMIDO)-2,4,6-TRIIODOPHENYL)-
RefChem:331239
DTXSID00945967
2-{3-[Acetyl(ethyl)amino]-2,4,6-triiodophenyl}butanoic acid