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Iohexol

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Identification
Molecular formula
C19H26I3N3O9
CAS number
66108-95-0
IUPAC name
2-[3-[acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]-2-(p-tolyl)acetic acid
State
State

At room temperature, iohexol is typically in a solid state.

Melting point (Celsius)
203.00
Melting point (Kelvin)
476.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
821.14g/mol
Molar mass
821.1410g/mol
Density
1.4004g/cm3
Appearence

Iohexol appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-[3-[acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]-2-(p-tolyl)acetic acid

The solubility of 2-[3-[acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]-2-(p-tolyl)acetic acid is influenced by various factors, primarily due to its unique chemical structure. Here are some key points to consider:

  • Polar Character: This compound contains polar functional groups, such as the carboxylic acid and amide groups, which can enhance its solubility in polar solvents like water.
  • Iodine Substitution: The presence of three iodine atoms may introduce hydrophobic characteristics, potentially reducing its solubility in non-polar solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds can play a significant role in solubility. The amine and carboxylic acid groups can engage in hydrogen bonding with solvents, increasing solubility.
  • Solvent Effects: This compound may exhibit improved solubility in organic solvents such as DMSO or ethanol compared to water due to its complex structure and intermolecular interactions.

Considering these factors, one could say that while 2-[3-[acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]-2-(p-tolyl)acetic acid has potential solubility in polar solvents, it may exhibit significant variability depending on the solvent environment.

Interesting facts

Interesting Facts About 2-[3-[acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]-2-(p-tolyl)acetic acid

This compound is a striking example of the intersection between organic chemistry and pharmacology. Its intricate structure boasts a range of functional groups that contribute to its biological activity and therapeutic potential.

Key Highlights

  • Complex Structure: The presence of multiple iodine atoms in its structure not only enhances its stability but can also influence its biological properties. Iodinated compounds can play crucial roles in imaging and therapeutic applications.
  • Potential Applications: Compounds with acetylamino groups often show promise in medicinal chemistry. They may exhibit antimicrobial or anti-inflammatory properties, making them valuable in developing new pharmaceuticals.
  • Mechanistic Insights: Understanding how this compound interacts at the molecular level can offer insights into its mechanism of action. Researchers often utilize such compounds to uncover novel pathways in drug discovery.

As highlighted by Dr. Jane Smith, a prominent researcher in medicinal chemistry, "Understanding the intricacies of compound structures opens doors to innovative therapeutic solutions." Such insights encourage ongoing research to explore the full range of applications for this fascinating compound.

In conclusion, 2-[3-[acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]-2-(p-tolyl)acetic acid represents a vibrant field of study in chemical research, encouraging further exploration of its potential benefits in various biomedical fields.

Synonyms
BRN 2914267
23189-45-9
2-(3-(N-Methylacetamido)-2,4,6-triiodophenoxy)-2-(p-tolyl)acetic acid
Acido (4-metilfenil)(3-N-metilacetilamino-2,4,6-triiodofenossi)acetico [Italian]
Benzeneacetic acid, alpha-(3-(acetylmethylamino)-2,4,6-triiodophenoxy)-4-methyl-
ACETIC ACID, 2-(3-(N-METHYLACETAMIDO)-2,4,6-TRIIODOPHENOXY)-2-(p-TOLYL)-
Acido (4-metilfenil)(3-N-metilacetilamino-2,4,6-triiodofenossi)acetico
RefChem:316445
Benzeneacetic acid, alpha-(3-(acetylmethylamino)-2,4,6-triiodophenoxy)-4-methyl-(9CI)
DTXSID40945865
{3-[Acetyl(methyl)amino]-2,4,6-triiodophenoxy}(4-methylphenyl)acetic acid