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Ioxaglic acid

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Identification
Molecular formula
C11H9I3NO4
CAS number
59017-02-0
IUPAC name
2-[3-[acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]acetic acid
State
State

The compound is a solid at room temperature, often provided in a powder or crystalline form for use in diagnostic imaging agents.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
420.00
Boiling point (Kelvin)
693.15
General information
Molecular weight
821.95g/mol
Molar mass
821.9460g/mol
Density
2.0190g/cm3
Appearence

Ioxaglic acid typically appears as an odorless, white, crystalline powder. It is often used in medical imaging and is known for its radiopaque properties. This makes it useful as a contrast agent in various radiographic procedures.

Comment on solubility

Solubility of 2-[3-[acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]acetic acid

The compound 2-[3-[acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]acetic acid, with the chemical formula C11H9I3NO4, exhibits some interesting solubility characteristics due to its complex structure. Here are some key points regarding its solubility:

  • Polar Functional Groups: The presence of polar groups, such as the acetyl and amino functionalities, may enhance the solubility in polar solvents.
  • Iodine Atoms: The three iodine atoms can lead to increased hydrophobic interactions, potentially reducing solubility in non-polar solvents.
  • Hydrogen Bonding: The compound's ability to form hydrogen bonds facilitates solubility in water and other protic solvents.
  • Solvent Compatibility: It may dissolve well in dimethyl sulfoxide (DMSO) or ethanol, but may face challenges in hexane.

Overall, solubility is influenced by the balance between the polar and non-polar characteristics of the compound. Understanding these factors is crucial for applications involving this chemical compound, making it vital for researchers to explore its solubility in various solvents.

Interesting facts

Exploring 2-[3-[Acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]acetic acid

The compound 2-[3-[acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]acetic acid is a fascinating example of an organoiodine compound, which has garnered interest in various scientific fields, particularly in medicinal chemistry and environmental studies. Here are some intriguing facts about this compound:

  • Organohalogen Chemistry: This compound contains triiodophenoxy groups that are noteworthy for their halogenation. The iodine atoms can influence the electronic properties and stability of the compound, making it a valuable subject in organohalogen chemistry.
  • Potential Biological Activity: The presence of the acetyl(methyl)amino group suggests potential pharmacological activities. Many derivatives of acetic acid show promise in drug development, particularly for their anti-inflammatory and analgesic properties.
  • Environmental Applications: Compounds with multiple halogens, including iodine, are studied for their environmental behavior and potential applications in waste management, specifically in the remediation of iodine-contaminated sites.
  • Research Utility: This compound may serve as a model for understanding the interactions and binding affinities of similar compounds in biological systems, particularly in receptor sites that recognize halogenated substances.
  • Complex Synthesis: The synthesis of this compound represents an interesting challenge due to the number of iodine atoms and the need for strategic functionalization, often requiring advanced synthetic techniques and careful manipulation of reaction conditions.

In conclusion, 2-[3-[acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]acetic acid is not just a chemical entity; it’s a gateway to exploring new realms of research in medicinal chemistry, environmental science, and advanced synthesis. Its unique structural features make it a compelling topic for both theoretical and practical discussions in the field of chemistry.

Synonyms
13080-24-5
BRN 2166049
ACETIC ACID, (3-(N-METHYLACETAMIDO)-2,4,6-TRIIODOPHENOXY)-
(3-(N-Methylacetamido)-2,4,6-triiodophenoxy)acetic acid
DTXSID50156748
DTXCID8079239
[3-(N-Methylacetylamino)-2,4,6-triiodophenoxy]acetic acid
2-[3-[acetyl(methyl)amino]-2,4,6-triiodophenoxy]acetic acid