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Iomeprol

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Identification
Molecular formula
C17H22I3N3O8
CAS number
78649-41-9
IUPAC name
2-[3-[acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid
State
State

At room temperature, Iomeprol is typically stored and used in solution form. In its pure state, it may be found as a solid powder. However, when utilized for imaging purposes, it is administered as a liquid because it is dissolved in water to create a solution suitable for injection or ingestion depending upon the diagnostic requirement.

Melting point (Celsius)
185.00
Melting point (Kelvin)
458.15
Boiling point (Celsius)
230.00
Boiling point (Kelvin)
503.15
General information
Molecular weight
777.09g/mol
Molar mass
777.0910g/mol
Density
1.4666g/cm3
Appearence

Iomeprol is an iodinated, non-ionic, water-soluble radiographic contrast medium. It is typically a white to off-white powder that is used in solution form for medical imaging. In solution, it can appear as a clear to pale yellow liquid depending on the concentration and formulation.

Comment on solubility

Solubility of 2-[3-[acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]hexanoic Acid

The solubility of 2-[3-[acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid can be intriguing due to its complex molecular structure, which influences its interactions with solvents. Factors that play a role in its solubility include:

  • Polarity: The compound contains both polar and nonpolar groups due to the presence of the carboxylic acid functional group and the aromatic rings, affecting its solubility profile in various solvents.
  • Hydrogen Bonding: The ability of the -COOH group to form hydrogen bonds may enhance solubility in polar solvents such as water.
  • Hydrophobic Interactions: The long hydrocarbon chain could lead to hydrophobic interactions, making the compound less soluble in polar solvents.
  • Temperature Dependence: As is common with many organic compounds, the solubility may vary significantly with temperature; higher temperatures may improve solubility.

In conclusion, the solubility of 2-[3-[acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid is likely to be poor in nonpolar solvents but could exhibit moderate solubility in polar solvents, especially at elevated temperatures. It’s essential to conduct experimental assessments to determine the precise solubility parameters in different media.

Interesting facts

Interesting Facts about 2-[3-[Acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]hexanoic Acid

2-[3-[Acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid is a fascinating compound with unique properties that make it of significant interest in the fields of chemistry and pharmacology. Here are some captivating aspects to note:

  • Complex Structure: The compound features a sophisticated molecular architecture, highlighted by the presence of multiple functional groups. Its structure includes a phenoxy group, which is well-known for its role in the design of herbicides and pharmaceutical agents.
  • Iodine Atoms: With three iodine atoms integrated into its molecular framework, this compound's iodine content may contribute to unique biochemical interactions. Iodine is often linked to enhancing radiolabeling for imaging techniques in medicinal chemistry.
  • Biological Relevance: The incorporation of acetyl(methyl)amino groups suggests potential biological activity. Such moieties are common in drug development as they can improve solubility and biological efficacy.
  • Therapeutic Potential: Due to its structural composition, this compound could exhibit interesting *antibacterial* or *antitumor* properties. Chemical modifications of similar compounds are often scrutinized for their ability to target specific biological pathways.
  • Environmental Implications: The compound's phenoxy component raises questions about its environmental impact, particularly in agricultural contexts where phenoxy herbicides have been both beneficial and controversial.

In summary, 2-[3-[acetyl(methyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid does not merely reflect a series of atoms but embodies *potential innovations* in biochemistry and pharmacology. As scientists continue to explore such compounds, their implications in drug design and environmental science may change our understanding of molecular interactions.

Synonyms
24340-19-0
BRN 2709587
2-(3-(N-Methylacetamido)-2,4,6-triiodophenoxy)hexanoic acid
HEXANOIC ACID, 2-(3-(N-METHYLACETAMIDO)-2,4,6-TRIIODOPHENOXY)-
RefChem:347663
DTXSID90947177
2-[[3-(N-Methylacetylamino)-2,4,6-triiodophenyl]oxy]hexanoic acid
2-{3-[Acetyl(methyl)amino]-2,4,6-triiodophenoxy}hexanoic acid