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Iopamidol

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Identification
Molecular formula
C17H22I3N3O8
CAS number
60166-93-0
IUPAC name
2-[3-[acetyl(propyl)amino]-2,4,6-triiodo-phenoxy]acetic acid
State
State

At room temperature, Iopamidol is in a solid state.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.15
Boiling point (Celsius)
315.00
Boiling point (Kelvin)
588.15
General information
Molecular weight
777.09g/mol
Molar mass
777.0880g/mol
Density
1.6650g/cm3
Appearence

Iopamidol is typically observed as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-[3-[acetyl(propyl)amino]-2,4,6-triiodo-phenoxy]acetic acid

The solubility of 2-[3-[acetyl(propyl)amino]-2,4,6-triiodo-phenoxy]acetic acid is an intriguing aspect that reflects the compound's complex structure and substituents. Understanding its solubility can provide insights into its potential applications and behavior in various environments.

Key Factors Influencing Solubility

  • Polarity: Due to its diverse functional groups, the polarity of the molecule plays a significant role in determining its solubility in different solvents. Polar solvents can enhance solubility, whereas nonpolar solvents may show limited interaction.
  • Hydrogen Bonding: The presence of acidic and amine groups suggests the possibility of hydrogen bonding, which can significantly affect the solubility behavior in aqueous solutions.
  • Size and Steric Hindrance: The bulky iodine substituents can cause steric effects that may hinder solubility, particularly in more hydrophobic environments.
  • pH Dependence: Since the compound contains acidic functionalities, its solubility may vary with pH, leading to different forms of the compound being soluble at various pH levels.

Overall, the solubility of 2-[3-[acetyl(propyl)amino]-2,4,6-triiodo-phenoxy]acetic acid can be summarized as:

  • Potentially soluble in polar solvents such as water or alcohols, depending on its ionization state.
  • Less soluble in nonpolar solvents due to the high molecular weight and polarity of certain groups.

This complex behavior emphasizes the need to analyze solubility through specific experimental conditions, ensuring appropriate use in scientific and industrial applications.

Interesting facts

Interesting Facts About 2-[3-[acetyl(propyl)amino]-2,4,6-triiodo-phenoxy]acetic acid

This compound is a fascinating example of how the integration of various functional groups can lead to unique properties and potential applications. With its complex structure, 2-[3-[acetyl(propyl)amino]-2,4,6-triiodo-phenoxy]acetic acid showcases several noteworthy aspects:

  • Structure Complexity: The presence of both acetyl and propyl amino groups adds to the versatility of this compound, making it a candidate for studies involving drug development and synthesis.
  • Triiodo Phenoxy Moiety: The incorporation of triiodo groups suggests interesting applications in the field of imaging and diagnostics, especially in medical research, due to iodine’s radiographic properties.
  • Biological Significance: Compounds similar to this one have been investigated for their potential biological functions, including antimicrobial and anticancer properties, making them significant in pharmaceutical research.
  • Environmental Impact: The careful study of such halogenated compounds is important in chemistry due to their possible environmental effects and roles in ecotoxicology.

As scientists continue to explore the capabilities of this compound, it may yield exciting results in medicinal chemistry, toxicology, and environmental science. The complexity and multifunctionality of 2-[3-[acetyl(propyl)amino]-2,4,6-triiodo-phenoxy]acetic acid truly exemplify the intricate beauty of chemical compounds.

Synonyms
BRN 2673413
24340-10-1
ACETIC ACID, (3-(N-PROPYLACETAMIDO)-2,4,6-TRIIODOPHENOXY)-
(3-(N-Propylacetamido)-2,4,6-triiodophenoxy)acetic acid
DTXSID90179077
RefChem:316191
DTXCID20101568