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Iopamidol

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Identification
Molecular formula
C17H22I3N3O8
CAS number
60166-93-0
IUPAC name
2-[3-[acetyl(propyl)amino]-2,4,6-triiodo-phenyl]acetic acid
State
State

At room temperature, Iopamidol is typically in a solid state. It is used in various applications including as a contrast agent in medical imaging, due to its stability and solubility in bodily fluids.

Melting point (Celsius)
199.00
Melting point (Kelvin)
472.15
Boiling point (Celsius)
245.80
Boiling point (Kelvin)
518.95
General information
Molecular weight
777.09g/mol
Molar mass
777.0880g/mol
Density
1.6350g/cm3
Appearence

Iopamidol appears as a white to off-white crystalline powder. It is typically odorless and has a characteristic solid appearance, which might slightly vary based on purity and form.

Comment on solubility

Solubility of 2-[3-[acetyl(propyl)amino]-2,4,6-triiodo-phenyl]acetic acid

This compound exhibits intriguing solubility characteristics due to its unique structure and functional groups. The presence of both the acetyl group and the ionic acid moiety significantly influences its solubility profile. Consider the following aspects:

  • Hydrophilicity: The carboxylic acid group can form hydrogen bonds with water, enhancing solubility in polar solvents.
  • Hydrophobic Regions: The propyl chain contributes hydrophobicity, which may limit solubility in highly polar solvents.
  • Effect of Iodine Atoms: The triiodo substituents may introduce steric hindrance and impact the overall solubility by making the compound bulkier.

As a result, its solubility might be optimal in moderately polar solvents while having limited solubility in pure water. A general guideline to keep in mind is:

The more intricate the structure, the more intricate the solubility behavior.

Understanding the balance between hydrophilic and hydrophobic interactions is crucial for predicting how this compound behaves in different environments. Further empirical testing may provide insights into its solubility under various conditions.

Interesting facts

Interesting Facts about 2-[3-[acetyl(propyl)amino]-2,4,6-triiodo-phenyl]acetic acid

This intriguing compound, known for its complex structure and diverse applications, merges various functional groups that contribute to its unique properties. Here are some fascinating insights about this chemical:

  • Triiodinated Phenyl Group: The presence of the triiodo group on the phenyl ring significantly enhances the compound's characteristics. Iodine is notable for its ability to increase the compound's radioactivity, which can be valuable in medical imaging and therapeutic applications.
  • Amine Functional Group: The acetyl(propyl)amino moiety demonstrates its potential as a pharmaceutical agent. Such substitutions can modulate the biological activity of compounds, indicating that this compound may have important implications in drug design.
  • Biological Relevance: Compounds with similar structures have been studied for their roles as potential anti-inflammatory or anticancer agents, making this compound an interesting subject for pharmacological research.
  • Applications in Research: Due to its distinctive structure, researchers may investigate its effects on biological systems, particularly in the fields of medicinal chemistry and toxicology.

In conclusion, 2-[3-[acetyl(propyl)amino]-2,4,6-triiodo-phenyl]acetic acid is not just a chemical notation; it represents a complex entity with valuable potential, opening pathways for innovation in both medicinal and chemical sciences. As scientists continue to explore its properties, the possibilities for its application are boundless!

Synonyms
BRN 3001019
29193-34-8
ACETIC ACID, (3-(N-PROPYLACETAMIDO)-2,4,6-TRIIODOPHENYL)-
(3-(N-Propylacetamido)-2,4,6-triiodophenyl)acetic acid
DTXSID00183448
RefChem:316192
DTXCID10105939