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Iopanoic acid

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Identification
Molecular formula
C11H9I3NO2
CAS number
96-83-3
IUPAC name
2-(3-amino-2,4,6-triiodo-phenyl)-2-phenyl-acetic acid
State
State
Iopanoic acid is a solid at room temperature, typically found in a crystalline form.
Melting point (Celsius)
228.00
Melting point (Kelvin)
501.15
Boiling point (Celsius)
362.40
Boiling point (Kelvin)
635.55
General information
Molecular weight
573.96g/mol
Molar mass
573.9640g/mol
Density
3.6000g/cm3
Appearence

Iopanoic acid appears as a white crystalline solid. It is typically odorless. The compound is often encountered as a powder in its pure form.

Comment on solubility

Solubility of 2-(3-amino-2,4,6-triiodo-phenyl)-2-phenyl-acetic acid

The solubility of 2-(3-amino-2,4,6-triiodo-phenyl)-2-phenyl-acetic acid in various solvents showcases its unique chemical characteristics. This compound, with its complex structure containing multiple iodine atoms, is likely to exhibit some fascinating solubility behaviors:

  • Polar Solvents: This compound may show a degree of solubility in polar solvents like water due to the presence of the amino group which can engage in hydrogen bonding.
  • Non-Polar Solvents: Conversely, its bulky aromatic groups and iodine atoms tend to make it more soluble in non-polar solvents, where it may dissolve more readily.
  • Concentration Effects: The solubility can vary significantly with temperature and concentration, making it important to conduct experiments under controlled conditions to ascertain precise values.
  • Complexation: There may also be a potential for complexation with certain cations or anions, influencing its overall solubility profile in mixed solvent systems.

It's important to note that, as with many compounds containing halogens, the solubility can be influenced by ionic strength and the presence of competing ions in solution. As such, careful evaluation through experimentation is essential to understand the precise solubility limits of this intriguing compound.

Interesting facts

Interesting Facts about 2-(3-amino-2,4,6-triiodo-phenyl)-2-phenyl-acetic acid

2-(3-amino-2,4,6-triiodo-phenyl)-2-phenyl-acetic acid, often referred to in the scientific community as a derivative of phenylacetic acid, showcases a fascinating synergy of organic and medicinal chemistry. Below are some intriguing aspects of this compound:

  • Stellar Iodine Substitution: The presence of iodine atoms in the compound not only impacts its chemical properties but also enhances its role in medical imaging as radioisotopes.
  • Amino Group Influence: The -NH2 (amino) group contributes significantly to the compound's reactivity and biological activity, potentially influencing receptor binding and drug efficacy.
  • Potential Therapeutic Applications: Compounds with similar structures have been studied for their potential use in treating various conditions, including cancer and inflammation, due to their unique biological activity.
  • Structure-Activity Relationship (SAR): The variation in substituent groups, like the triiodo-phenyl moiety, makes this compound an excellent candidate for SAR studies, helping chemists design more effective pharmaceuticals.
  • Research Significance: The compound may serve as a lead compound in drug discovery, offering avenues to synthesize newer derivatives with improved properties.

As a highlight of its chemical structure, the presence of multiple iodine atoms has garnered interest due to their unique electron-withdrawing effects, which can stabilize various reactive intermediates. Furthermore, the conjugated system created by the aromatic rings promises intriguing photophysical behavior, which can be explored in advanced materials science. As articulated by renowned chemists, "The beauty of organic synthesis lies in the myriad ways we can manipulate molecular structures to unveil hidden functionalities." This compound exemplifies this principle and opens doors to exciting chemical exploration!