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Iodixanol

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Identification
Molecular formula
C19H29I3N3O9
CAS number
92339-11-2
IUPAC name
2-[(3-amino-2,4,6-triiodo-phenyl)methyl-(carboxymethyl)amino]acetic acid
State
State

At room temperature, Iodixanol exists in solid form. However, for its primary application as a contrast agent, it is commonly used in the form of an aqueous solution.

Melting point (Celsius)
164.00
Melting point (Kelvin)
437.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
789.13g/mol
Molar mass
789.1300g/mol
Density
2.0200g/cm3
Appearence

Iodixanol is typically a white or off-white crystalline powder. It is often available in solution form for medical imaging purposes and appears as a clear, colorless to slightly yellow solution.

Comment on solubility

Solubility of 2-[(3-amino-2,4,6-triiodo-phenyl)methyl-(carboxymethyl)amino]acetic acid

The solubility of 2-[(3-amino-2,4,6-triiodo-phenyl)methyl-(carboxymethyl)amino]acetic acid exhibits some interesting characteristics due to its complex structure. This compound contains both hydrophilic and hydrophobic domains, which can significantly influence its solubility in various solvents.

Key Factors Affecting Solubility:

  • Functional Groups: The presence of carboxymethyl and amino groups typically enhances solubility in polar solvents, such as water, allowing for potential interactions through hydrogen bonding.
  • Iodine Atoms: The triiodo-substituents may introduce some hydrophobic characteristics, which could limit solubility in non-polar solvents.
  • pH Levels: The solubility may vary with changes in pH, as the protonation state of the amino groups can modulate their protonation and therefore solubility pathways.

In general, the solubility profile of this compound can be summarized as follows:

  • High Solubility: Expected in aqueous solutions due to the ionizable carboxylic acid group.
  • Limited Solubility: May occur in organic solvents given the presence of iodinated rings.

Understanding the solubility of this compound is crucial for its practical applications, particularly in pharmaceutical formulations where effective dissolution is essential for bioavailability. As with many compounds, considering the interplay of its physicochemical properties provides deeper insights into its behavior in various environments.

Interesting facts

Interesting Facts about 2-[(3-amino-2,4,6-triiodo-phenyl)methyl-(carboxymethyl)amino]acetic acid

This intriguing compound belongs to a class of chemical entities known as iodinated amino acids. The presence of iodine in its structure not only imparts unique properties but also significantly enhances its utility in various applications.

Key Characteristics

  • Halogenation: The incorporation of three iodine atoms on the phenyl ring makes this compound a candidate for radiolabeling, a technique widely utilized in medical imaging.
  • Amino Acid Structure: As a derivative of an amino acid, this compound can serve as a useful building block in peptide synthesis and biological research.
  • Biological Significance: Compounds containing iodine, such as this one, are often investigated for their effects on metabolic pathways and potential therapeutic roles.
  • Pharmaceutical Applications: Due to its unique structure, this compound may have applications in drug design, particularly in targeting specific biological pathways or receptors.

Research Insights

Researchers are particularly interested in the following aspects:

  • Therapeutic Potential: The modifiable nature of the carboxymethyl group could lead to variants that improve binding affinities to biological targets.
  • Environmental Impact: As the field of environmental chemistry grows, the effects of iodine-containing compounds on ecosystems are rapidly being explored.
  • Innovative Techniques: In laboratories, this compound allows chemists to experiment with new synthesis methods and explore the limits of chemical reaction pathways.

In summary, 2-[(3-amino-2,4,6-triiodo-phenyl)methyl-(carboxymethyl)amino]acetic acid stands out as a multifaceted organic compound with profound implications across various scientific domains. Its intersection of chemistry and medicine exemplifies the marvels of molecular innovation. As stated by a renowned chemist, "The true beauty of chemistry lies in its ability to connect disparate worlds—from the laboratory bench to the human body."

Synonyms
BRN 3004169
ACETIC ACID, ((3-AMINO-2,4,6-TRIIODOBENZYL)IMINO)DI-
((3-Amino-2,4,6-triiodobenzyl)imino)diacetic acid
N-(2,4,6-Triiodo-3-aminobenzyl)iminodiacetic acid
19014-76-7
DTXSID80172491
DTXCID6094982