Skip to main content

Iodixanol

ADVERTISEMENT
Identification
Molecular formula
C35H44I6N6O15
CAS number
92339-11-2
IUPAC name
2-[(3-amino-2,4,6-triiodo-phenyl)methyl]hexanedioic acid
State
State

At room temperature, iodixanol is a solid. It is stable under normal conditions and does not readily volatilize.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
1550.14g/mol
Molar mass
1 550.1370g/mol
Density
2.1050g/cm3
Appearence

Iodixanol is typically a white to off-white crystalline powder. It is often used as a contrast agent and is highly soluble in water.

Comment on solubility

Solubility of 2-[(3-amino-2,4,6-triiodo-phenyl)methyl]hexanedioic acid

The solubility of 2-[(3-amino-2,4,6-triiodo-phenyl)methyl]hexanedioic acid can be analyzed considering its structural components and functional groups. Generally, the solubility of compounds like this can be impacted by various factors:

  • Polarity: The presence of multiple iodine atoms and an amino group suggests that the compound may exhibit significant polarity, typically enhancing solubility in polar solvents.
  • Hydrogen Bonding: The amino group (-NH2) can engage in hydrogen bonding, which increases solubility in water and other polar solvents.
  • Sterics: The bulky iodine substituents may hinder interactions with solvents, possibly affecting overall solubility.

Hence, while 2-[(3-amino-2,4,6-triiodo-phenyl)methyl]hexanedioic acid might dissolve well in polar solvents due to hydrogen bonding, its solubility in non-polar solvents is likely to be low. It is important to note that experimental data is essential for verifying these solubility characteristics.

Interesting facts

Interesting Facts about 2-[(3-amino-2,4,6-triiodo-phenyl)methyl]hexanedioic acid

This fascinating compound belongs to a class of chemical substances known for their unique structural features and biological properties. 2-[(3-amino-2,4,6-triiodo-phenyl)methyl]hexanedioic acid is particularly notable due to its incorporation of iodine, a halogen known for its important role in various biological applications.

Key Characteristics

  • Iodine Presence: The presence of three iodine atoms enhances the compound's radiopacity, making it valuable in medical imaging and diagnostic applications.
  • Amino Group: The amino functional group contributes to the compound's potential biological activity, possibly influencing protein interactions and metabolic pathways.
  • Carboxylic Acid Functionality: The hexanedioic acid moiety provides acidity, making it a useful compound in various chemical reactions and synthesis processes.

Applications and Significance

In pharmaceutical chemistry, this compound is of interest owing to its potential as a tracer in imaging techniques or as a derivative in drug development. The iodine atoms can serve as markers, thus enhancing visibility in medical scans.

Furthermore, due to the structural diversity offered by the combination of an amino group and multiple iodine substitutions, researchers are prompted to explore structure-activity relationships. This could lead to insights into how variations in structure impact biological response, paving the way for the development of new therapeutic agents.

As one delves into the chemistry of 2-[(3-amino-2,4,6-triiodo-phenyl)methyl]hexanedioic acid, it is an example of how specific functional groups and halogen substitution can lead to compounds with enhanced properties, opening new avenues in medical and chemical research.

Synonyms
BRN 3038760
13072-73-6
2-(3-Amino-2,4,6-triiodobenzyl)adipic acid
Hexanedioic acid, 2-(3-amino-2,4,6-triiodobenzyl)-
Acido 2-(3-amino-2,4,6-triiodobenzil)adipico [Italian]
ADIPIC ACID, 2-(3-AMINO-2,4,6-TRIIODOBENZYL)-
Acido 2-(3-amino-2,4,6-triiodobenzil)adipico
2-[(3-amino-2,4,6-triiodophenyl)methyl]hexanedioic acid
DTXSID10926868