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N-(3-amino-4-hydroxyphenyl)sulfanilamide

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Identification
Molecular formula
C13H12N2O5S
CAS number
59901-73-4
IUPAC name
2-[(3-amino-4-hydroxy-phenyl)sulfonylamino]benzoic acid
State
State

At room temperature, the compound is in a solid state, usually in the form of a powder. It remains stable under normal handling and storage conditions.

Melting point (Celsius)
208.00
Melting point (Kelvin)
481.15
Boiling point (Celsius)
343.00
Boiling point (Kelvin)
616.15
General information
Molecular weight
292.31g/mol
Molar mass
292.3000g/mol
Density
1.5676g/cm3
Appearence

The compound generally appears as a white to pale yellow powder or crystalline solid. It may exhibit slight beige hues depending on the specific batch and purity.

Comment on solubility

Solubility of 2-[(3-amino-4-hydroxy-phenyl)sulfonylamino]benzoic acid

The solubility of 2-[(3-amino-4-hydroxy-phenyl)sulfonylamino]benzoic acid (C13H12N2O5S) can be influenced by various factors due to its unique chemical structure. This compound contains both acidic and basic functional groups, which can enhance its ability to interact with solvent molecules.

Factors Affecting Solubility:

  • Polarity: The presence of sulfonamide and hydroxyl groups makes it relatively polar, likely increasing solubility in polar solvents such as water.
  • pH Levels: As a compound with carboxylic acid functional groups, its solubility may increase in alkaline environments where deprotonation occurs.
  • Temperature: Higher temperatures typically increase solubility for many organic compounds, including this acid.
  • Hydrogen Bonding: The ability of the molecule to form hydrogen bonds enhances solubility in solvents that can accommodate such interactions.

In general, compounds like 2-[(3-amino-4-hydroxy-phenyl)sulfonylamino]benzoic acid are typically expected to exhibit increased solubility in aqueous solutions compared to less polar organic solvents. The overall solubility profile can be summarized as: polar solvents = high solubility; nonpolar solvents = low solubility.

Interesting facts

Interesting Facts About 2-[(3-Amino-4-Hydroxy-Phenyl)Sulfonylamino]Benzoic Acid

This intriguing compound, commonly known in pharmaceutical research, boasts a unique structure that enhances its biological activity. Here are several key insights about it:

  • Pharmaceutical Relevance: This compound is often investigated for its potential as a therapeutic agent due to its ability to interact with various biological targets.
  • Functional Groups: The presence of amino and sulfonamide functional groups contributes to the compound's pharmacological properties, making it an interesting subject for drug design.
  • Structural Diversity: The combination of a benzoic acid moiety with sulfonamide and amino groups showcases the structural diversity observed in medicinal chemistry.
  • Potential Applications: Research indicates that this compound may have applications in treating conditions such as inflammation and cancer, owing to its ability to inhibit key enzymes in disease pathways.

Furthermore, scientists are continuously exploring derivatives of this compound in hopes of enhancing efficacy and reducing side effects. As noted by renowned chemists, "The modification of molecular structures can lead to potential improvements in therapeutic performance." Its rich chemistry not only helps in understanding molecular interactions but also lays the groundwork for the discovery of novel compounds with improved biological functions.

In conclusion, 2-[(3-amino-4-hydroxy-phenyl)sulfonylamino]benzoic acid stands as a promising molecule, reflecting the intricate relationship between chemistry and pharmacology in addressing complex health challenges.

Synonyms
91-35-0
2-(3-Amino-4-hydroxyphenylsulfonamido)benzoic acid
2-[[(3-Amino-4-hydroxyphenyl)sulphonyl]amino]benzoic acid
2-[(3-amino-4-hydroxyphenyl)sulfonylamino]benzoic acid
Benzoic acid, 2-[[(3-amino-4-hydroxyphenyl)sulfonyl]amino]-
N-(4-Hydroxymetanilyl)anthranilic acid
37SPR6R44N
EINECS 202-063-1
Anthranilic acid, N-(3-amino-4-hydroxyphenylsulfonyl)-
2-{[(3-amino-4-hydroxyphenyl)sulfonyl]amino}benzoic acid
DTXSID6059023
Benzoic acid, 2-(((3-amino-4-hydroxyphenyl)sulfonyl)amino)-
EC 202-063-1
ANTHRANILIC ACID, N-(4-HYDROXYMETANILYL)-
2-(((3-Amino-4-hydroxyphenyl)sulphonyl)amino)benzoic acid
2-(((3-AMINO-4-HYDROXYPHENYL)SULFONYL)AMINO)BENZOIC ACID
2-[[(3-Amino-4-hydroxyphenyl)sulfonyl]amino]benzoic acid
MFCD00087624
UNII-37SPR6R44N
2-(3-Amino-4-hydroxyphenylsulfonamido)benzoicacid
SCHEMBL2605789
DTXCID0048715
ISDVREGLMJJFJG-UHFFFAOYSA-N
AKOS001036245
AC-11898
CS-0358312
NS00004282
F15529
2-(3-amino-4-hydroxybenzenesulfonamido)benzoic acid
2-((3-Amino-4-hydroxyphenyl)sulfonamido)benzoic acid
Q27256699