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Fenbufen

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Identification
Molecular formula
C16H12O3
CAS number
36330-85-5
IUPAC name
2-(3-benzoylanilino)benzoic acid
State
State

At room temperature, Fenbufen is in a solid state. It is non-volatile and stable, common among benzoic acid derivatives.

Melting point (Celsius)
190.00
Melting point (Kelvin)
463.15
Boiling point (Celsius)
438.00
Boiling point (Kelvin)
711.15
General information
Molecular weight
254.27g/mol
Molar mass
254.2610g/mol
Density
1.3429g/cm3
Appearence

Fenbufen is a white crystalline solid. It belongs to the class of nonsteroidal anti-inflammatory drugs (NSAIDs). Its appearance is typical of many crystalline organic compounds, characterized by a solid form composed of well-organized molecular structures.

Comment on solubility

Solubility of 2-(3-benzoylanilino)benzoic acid

2-(3-benzoylanilino)benzoic acid is known for its intriguing solubility characteristics, which can be influenced by several factors:

  • Solvent Polarity: Generally, this compound shows a tendency to exhibit better solubility in polar organic solvents due to its extensive hydrogen bonding potential.
  • pH Influence: The solubility may change significantly with pH; in acidic conditions, the carboxylic acid group is likely to remain protonated, whereas in basic conditions, it can ionize, enhancing its solubility.
  • Temperature Effects: Increasing temperature typically improves the solubility of organic compounds, including this benzoic acid derivative.

Moreover, the presence of the aromatic rings can lead to π-π interactions with other solutes, influencing solubility in complex mixtures. As such, it’s essential to consider the specific solvent environment when preparing solutions of this intriguing compound.

In summary, the solubility of 2-(3-benzoylanilino)benzoic acid is not straightforward, as it can vary according to:

  1. Choice of solvent
  2. pH of the solution
  3. Temperature conditions

This complexity adds to the compound's unique chemistry and potential applications in organic synthesis and pharmaceuticals.

Interesting facts

Interesting Facts about 2-(3-benzoylanilino)benzoic acid

2-(3-benzoylanilino)benzoic acid is a fascinating compound that showcases the intricate world of organic chemistry. Known for its complex structure and varied applications, this compound is primarily of interest in the realms of pharmaceuticals and material science. Here are some intriguing aspects:

  • Structural Complexity: This compound features a dual aromatic system, which contributes to its unique chemical properties. The presence of both the benzoic acid group and the benzoylaniline moiety gives it a versatile linkage.
  • Applications in Medicine: Compounds of this type are often investigated for their potential medicinal properties, including anti-inflammatory and analgesic effects. Researchers are keen on exploring how such compounds can influence biological pathways.
  • Chemical Reactions: 2-(3-benzoylanilino)benzoic acid can participate in various chemical transformations. Its functionality allows it to engage in reactions such as esterification and amidation, paving the way for the synthesis of a myriad of derivatives.
  • Research Interest: The compound is a subject of many studies targeting drug design and development due to its potential to act as a lead compound. Its effectiveness can inspire modifications that enhance therapeutic efficacy.
  • Analytical Chemistry: The analysis and characterization of this compound often utilize techniques such as NMR and mass spectrometry, which allow scientists to elucidate its structure and confirm purity.

In summary, 2-(3-benzoylanilino)benzoic acid is not just a simple molecular entity but a gateway to numerous possibilities in chemical research and development. It stands as a testament to the creativity and complexity inherent in the field of chemistry.

Synonyms
N-(3-Benzoylphenyl)anthranilic acid
21003-80-5
BRN 2755095
ANTHRANILIC ACID, N-(3-BENZOYLPHENYL)-
DTXSID50175212
RefChem:319811
DTXCID9097703
2-[(3-Benzoylphenyl)amino]benzoic acid