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Ketoprofen

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Identification
Molecular formula
C16H14O3
CAS number
22071-15-4
IUPAC name
2-(3-benzoylphenyl)acetic acid
State
State

At room temperature, Ketoprofen is in a solid state.

Melting point (Celsius)
94.00
Melting point (Kelvin)
367.15
Boiling point (Celsius)
397.90
Boiling point (Kelvin)
671.05
General information
Molecular weight
254.28g/mol
Molar mass
254.2800g/mol
Density
1.2040g/cm3
Appearence

Ketoprofen typically appears as a white or almost white crystalline powder. It is often odourless or may have a faint characteristic odor.

Comment on solubility

Solubility of 2-(3-benzoylphenyl)acetic acid

2-(3-benzoylphenyl)acetic acid, a compound with intriguing properties, presents specific solubility characteristics that are essential for its applications in various fields. Understanding its solubility can help in predicting how this compound behaves in different environments:

  • Solvent Interactions: This compound tends to be more soluble in organic solvents such as ethanol, methanol, and acetone compared to water. This is largely due to its aromatic structure, which can engage in π-π stacking and hydrophobic interactions.
  • Aqueous Solubility: In water, the solubility of 2-(3-benzoylphenyl)acetic acid is relatively low. However, it can be facilitated by adjusting pH levels, as the carboxylic acid group allows for ionization under basic conditions, thus enhancing solubility.
  • pH Dependency: At low pH, the compound remains in its non-ionized form, which is typically less soluble in water, while higher pH levels can boost its ionization and increase solubility.
  • Temperature Effects: Increased temperatures generally promote solubility; thus, heating solvents may dissolve 2-(3-benzoylphenyl)acetic acid more effectively than at room temperature.

In summary, factors such as solvent choice, pH levels, and temperature play significant roles in determining the solubility of 2-(3-benzoylphenyl)acetic acid. Such knowledge is critical when utilizing this compound in various chemical or pharmaceutical applications.

Interesting facts

Interesting Facts About 2-(3-benzoylphenyl)acetic Acid

2-(3-benzoylphenyl)acetic acid, often referred to in research and industrial applications, is a fascinating organic compound with several noteworthy features:

  • Pharmaceutical Importance: This compound is a notable intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to interact effectively with specific biological targets.
  • Analytical Applications: Due to its specific properties, 2-(3-benzoylphenyl)acetic acid is widely used in analytical chemistry, especially in the development of methods for detecting and quantifying other chemical substances.
  • Structure-Activity Relationship: The compound's structure showcases how slight modifications can significantly alter biological activity, making it a valuable study material in medicinal chemistry.
  • Research Relevance: Ongoing studies are investigating its potential antioxidant properties, which may open new avenues for health-related applications.
  • Aesthetic Chemistry: The presence of the benzoyl phenyl group contributes to the compound's interesting chemical behavior, leading to various reactions that can be utilized in synthetic organic chemistry.

As a student of chemistry, grasping the multi-faceted applications of 2-(3-benzoylphenyl)acetic acid encourages an appreciation for how intricate chemical structures play essential roles in diverse scientific fields. As emphasized by renowned chemists, "Understanding the building blocks of chemistry is key to unlocking the mysteries of life itself," illustrating the importance of compounds like this one in advancing both research and practical applications.

Synonyms
3-Benzoylphenylacetic acid
2-(3-Benzoylphenyl)acetic acid
(3-Benzoylphenyl)acetic acid
3-Benzoylbenzeneacetic acid
57OG4Q7B6Y
EINECS 244-760-3
RU-4462
BRN 2647970
UNII-57OG4Q7B6Y
DTXSID10176563
KETOPROFEN IMPURITY B [EP IMPURITY]
KETOPROFEN IMPURITY B (EP IMPURITY)
RefChem:69097
DTXCID7099054
ALDSXDRDRWDASQ-UHFFFAOYSA-N
22071-22-3
Desmethyl Ketoprofen
m-Benzoylphenylacetic acid
Benzeneacetic acid, 3-benzoyl-
MFCD00046549
RU 4462
ACETIC ACID, (m-BENZOYLPHENYL)-
CHEMBL561718
19421 R.P.
Ketoprofen EP Impurity B
Ketoprofen Imp. B (EP); (3-Benzoylphenyl)acetic Acid; 2-(3-Benzoylphenyl)acetic acid; RU 4462; m-Benzoylphenylacetic acid; Ketoprofen Impurity B
3-Benzoylphenyl acetic acid
m-benzoyl-phenyl acetic acid
SCHEMBL512838
2-(3-Benzoylphenyl)aceticacid
BDBM50295286
AKOS016001230
AC-25584
DS-12292
SY019834
DB-045781
HY-131118
CS-0128784
NS00027043
F218362
Q27261516
(3-Benzoylbenzene)acetic acid;(3-Benzoylphenyl)acetic acid;2-(3-Benzoylphenyl)acetic acid