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Reboxetine

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Identification
Molecular formula
C19H23N3
CAS number
98769-84-7
IUPAC name
2-(3-benzyl-3,9-diazabicyclo[3.3.1]nonan-9-yl)-N,N-diethyl-ethanamine
State
State

At room temperature, Reboxetine is in a solid state.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
408.15
Boiling point (Kelvin)
681.30
General information
Molecular weight
314.46g/mol
Molar mass
314.4610g/mol
Density
1.2000g/cm3
Appearence

Reboxetine is a white to off-white crystalline powder. It is generally not hygroscopic and is soluble in water and alcohol, sparingly soluble in chloroform, and practically insoluble in hexane.

Comment on solubility

Solubility of 2-(3-benzyl-3,9-diazabicyclo[3.3.1]nonan-9-yl)-N,N-diethyl-ethanamine

The solubility characteristics of 2-(3-benzyl-3,9-diazabicyclo[3.3.1]nonan-9-yl)-N,N-diethyl-ethanamine are influenced by its unique molecular structure, which contains both hydrophobic and hydrophilic regions. This dual nature can lead to a complex solubility profile. Key considerations for solubility include:

  • Polarity: The presence of multiple functional groups may increase the polarity of the compound, enhancing its ability to dissolve in polar solvents.
  • Solvent Interaction: This compound is expected to have better solubility in organic solvents such as ethanol or methanol, compared to water.
  • Temperature Dependence: Like many organic compounds, the solubility may increase with temperature, leading to higher dissolution rates.
  • Complex Formation: The potential to form complexes with other molecules can also affect solubility, potentially increasing it under certain conditions.

In general, slightly soluble to moderately soluble descriptors may be applicable for this compound, depending on the specific conditions such as solvent choice and temperature. Understanding the solubility profile of this compound is crucial for applications in pharmaceuticals and chemical synthesis, where solubility can significantly impact bioavailability and reactivity.

Interesting facts

Interesting Facts about 2-(3-benzyl-3,9-diazabicyclo[3.3.1]nonan-9-yl)-N,N-diethyl-ethanamine

This compound is a fascinating example of a complex organic molecule due to its unique structure, featuring a bicyclic framework that envelops a nitrogen atom. Here are some compelling points regarding its significance:

  • Structural Diversity: The presence of a bicyclic system in its structure makes this compound notably interesting. Bicyclic compounds can exhibit unique chemical and physical properties due to their constrained geometry.
  • Potential Biological Activity: Compounds like this one, with multiple nitrogen atoms, have been investigated for various pharmacological activities. They often show promise as potential pharmaceuticals, especially in neuropharmacology.
  • Substituent Influence: The benzyl group attached to the bicyclic nitrogen can influence the compound’s reactivity and biological interactions. This makes studying such substituents critical in medicinal chemistry.
  • Applications in Synthesis: Such intricate compounds are not just theoretical; they may serve as intermediates in the synthesis of more complex pharmaceuticals. Their unique structure can be leveraged to develop new compounds with desirable biological effects.
  • Chiral Centers: If this compound contains chiral centers, it opens up discussions about stereoisomerism. The activity and behavior of each isomer can vary significantly, making it essential in drug development.
  • Research Interest: The study of such nitrogen-rich compounds is currently a hot topic in research, with ongoing studies exploring their roles in catalysis, material sciences, and biological systems.

As a noteworthy member of the amine family, this compound showcases the intricacies of organic chemistry, blending structural elegance with potential utility. Its study paves the way for innovations across various chemical disciplines.