Skip to main content

Iomeprol

ADVERTISEMENT
Identification
Molecular formula
C17H22I3N3O4
CAS number
78649-41-9
IUPAC name
2-[3-[benzyl(butanoyl)amino]-2,4,6-triiodo-phenyl]acetic acid
State
State

At room temperature, Iomeprol is a solid. It is usually processed in a dry form, suitable for preparation into injectable solutions.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
777.09g/mol
Molar mass
777.0930g/mol
Density
1.4780g/cm3
Appearence

Iomeprol generally appears as a white to slightly yellowish powder. It is odorless and has a crystalline structure.

Comment on solubility

Solubility of 2-[3-[benzyl(butanoyl)amino]-2,4,6-triiodo-phenyl]acetic acid

The solubility of 2-[3-[benzyl(butanoyl)amino]-2,4,6-triiodo-phenyl]acetic acid can be influenced by several factors due to its complex structure. Understanding its solubility characteristics is essential for applications in medicinal chemistry and formulation development.

Factors Affecting Solubility:

  • Polarity: The presence of the triiodo substituents can enhance hydrophobicity, potentially leading to lower solubility in aqueous environments.
  • Functional Groups: The carboxylic acid group may impart some hydrophilic characteristics, allowing for partial solubility in polar solvents.
  • Temperature: As with many compounds, increasing the temperature can generally boost solubility in solvents.

Generally, compounds like this that possess both hydrophilic and hydrophobic characteristics can exhibit:

  • Higher Solubility: In organic solvents such as dimethyl sulfoxide (DMSO) or ethanol.
  • Moderate Solubility: In water, depending on the pH and ionic strength of the solution.

In summary, while the solubility of 2-[3-[benzyl(butanoyl)amino]-2,4,6-triiodo-phenyl]acetic acid may not be uniformly high across all solvents, it is influenced by the intricate balance between its hydrophilic and hydrophobic properties. As a result, experimental determination is often necessary to accurately assess its solubility in specific conditions.

Interesting facts

Interesting Facts about 2-[3-[benzyl(butanoyl)amino]-2,4,6-triiodo-phenyl]acetic acid

This unique compound, with its complex structure, belongs to a class of molecules known as iodine-containing compounds. Iodine is not only essential for human health but also plays a critical role in modern medicine, particularly in imaging and therapeutic applications. Here are some captivating aspects of this compound:

  • Medicinal Potential: The presence of iodine in its structure positions this compound as a potential candidate for radiopharmaceuticals. Compounds containing iodine are often employed in diagnostics, especially in thyroid-related imaging.
  • Unique Structural Features: The benzyl (a type of aromatic ring bound to a CH2 group) coupled with a butanoyl moiety enhances the lipophilicity of the compound, potentially influencing its bioavailability and affinity to biological targets.
  • Applications in Drug Design: The intricate arrangement of amino acids in its structure may provide insight into designing new drugs or modifying existing therapies, particularly for conditions where iodine is beneficial.
  • Triiodo Functionality: The three iodine atoms attached to the phenyl group introduce significant electron-withdrawing properties. This feature is noteworthy as it can influence the compound's reactivity and interaction with various biological macromolecules.
  • Historical Context: Iodine compounds have a long history in medicinal chemistry, dating back to the 19th century when they were first recognized for their antibacterial properties. This compound continues this legacy in modern scientific exploration.

In essence, 2-[3-[benzyl(butanoyl)amino]-2,4,6-triiodo-phenyl]acetic acid stands at the intersection of medicinal chemistry and advanced drug design, providing exciting avenues for research and application. Its unique characteristics accentuate the beauty and complexity of chemical compounds in the realm of science.

Synonyms
BRN 3015992
Acetic acid, (3-(N-benzylbutyramido)-2,4,6-triiodophenyl)-
29193-41-7
(3-(N-Benzylbutyramido)-2,4,6-triiodophenyl)acetic acid
DTXSID70183455
RefChem:316182
DTXCID80105946