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Diethylaminoethanol hydrochloride

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Identification
Molecular formula
C8H20ClNO
CAS number
300-92-5
IUPAC name
[2-(3-benzyloxyanilino)-2-oxo-ethyl]-diethyl-ammonium;chloride
State
State

At room temperature, diethylaminoethanol hydrochloride is a solid.

Melting point (Celsius)
130.00
Melting point (Kelvin)
403.15
Boiling point (Celsius)
337.60
Boiling point (Kelvin)
610.80
General information
Molecular weight
191.70g/mol
Molar mass
191.7000g/mol
Density
1.0574g/cm3
Appearence

Diethylaminoethanol hydrochloride appears as a white to off-white crystalline powder. It is hygroscopic, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of [2-(3-benzyloxyanilino)-2-oxo-ethyl]-diethyl-ammonium;chloride

The compound [2-(3-benzyloxyanilino)-2-oxo-ethyl]-diethyl-ammonium;chloride exhibits interesting solubility characteristics that can influence its practical applications.

Water Solubility

This compound is generally soluble in water, primarily due to the presence of the quaternary ammonium structure. Here are some key factors affecting its solubility:

  • Ionization: The chloride ion contributes to a strong ionic interaction with water molecules.
  • Hydrogen Bonding: The benzyloxyaniline moiety can engage in hydrogen bonding, enhancing solubility.
  • Polarity: The overall polar nature of the compound facilitates solvation in aqueous environments.

Solubility in Organic Solvents

On the other hand, the compound may present limited solubility in non-polar organic solvents. This is largely due to:

  • Non-polar interactions: The benzyl group adds a hydrophobic character that can reduce solubility in purely non-polar solvents.
  • Chain length: The diethyl group's length may contribute to the steric hindrance, impacting dissolution in organic matrices.

As a result, the overall solubility of this compound is a balance between its ionic nature and hydrophobic features. It is essential to consider these attributes when formulating solutions that may include this compound, as they can dramatically affect bioavailability and interaction with other substances.

Interesting facts

Interesting Facts about [2-(3-Benzyloxyanilino)-2-Oxo-Ethyl]-Diethyl-Ammonium Chloride

This compound, with its complex structure, is a fascinating example of modern chemistry that blends organic synthesis with medicinal applications. Here are some interesting aspects to consider:

  • Synthetic Versatility: As a quaternary ammonium compound, it plays a pivotal role in various organic reactions, showcasing the versatility of ammonium salts in synthesis.
  • Potential Pharmacological Applications: Compounds of this nature often exhibit biological activity, making them of interest in pharmaceutical research. Their unique structures allow them to interact with biological membranes, possibly influencing drug delivery systems.
  • Research Interest: Due to the presence of the benzyloxy group, this compound is a subject of study for its potential as a *protective group* in organic reactions, illustrating its dual role in both structural and functional chemistry.
  • Importance of Functional Groups: The combination of the diethylammonium and the oxo-ethyl functional groups indicates potential properties that might be exploited in therapies concerning cell membranes or receptor binding.

To quote the famous chemist Linus Pauling, “Science is the search for truth.” In this case, the quest for understanding how compounds like [2-(3-Benzyloxyanilino)-2-Oxo-Ethyl]-Diethyl-Ammonium Chloride interact at the molecular level is a testament to the ongoing journey in chemical research.

In summary, this compound exemplifies how the interplay of various functional groups can lead to innovative uses in science and medicine. Continued exploration may yield exciting discoveries about its properties and potential applications.

Synonyms
19514-90-0
(3'-Benzyloxy-2-diethylamino)acetanilide hydrochloride
S 254
ACETANILIDE, 3'-BENZYLOXY-2-DIETHYLAMINO-, HYDROCHLORIDE
RefChem:315772