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2-(3-Bromo-4-butoxyphenyl)ethanehydroxamic acid

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Identification
Molecular formula
C12H16BrNO3
CAS number
213629-14-8
IUPAC name
2-(3-bromo-4-butoxy-phenyl)ethanehydroxamic acid
State
State

At room temperature, 2-(3-bromo-4-butoxyphenyl)ethanehydroxamic acid is generally found in a solid state. It is stable under ambient conditions, provided it is stored properly to avoid contact with moisture or excessive heat.

Melting point (Celsius)
129.00
Melting point (Kelvin)
402.15
Boiling point (Celsius)
529.00
Boiling point (Kelvin)
802.15
General information
Molecular weight
302.17g/mol
Molar mass
302.1690g/mol
Density
1.3870g/cm3
Appearence

The compound 2-(3-bromo-4-butoxyphenyl)ethanehydroxamic acid typically appears as a solid crystalline substance. Solid samples are often white to off-white in color and can form fine powder-like or crystalline structures.

Comment on solubility

Solubility of 2-(3-bromo-4-butoxy-phenyl)ethanehydroxamic acid

The solubility of 2-(3-bromo-4-butoxy-phenyl)ethanehydroxamic acid in various solvents is a crucial consideration for its application in chemical processes and formulations. Here are some key points regarding its solubility:

  • Polar Solvents: Due to the presence of the hydroxamic acid functional group, this compound is likely more soluble in polar solvents such as water and alcohols. The hydroxyl group can engage in hydrogen bonding, which significantly increases solubility in polar media.
  • Non-Polar Solvents: The bulky butoxy group may hinder solubility in non-polar solvents like hexane or toluene. The presence of aromatic ring structures, however, can enhance solubility to some extent due to π-π interactions.
  • Influence of pH: The solubility might also be affected by the pH of the solution. In acidic conditions, the hydroxamic acid can be protonated, which could affect its overall solubility profile.
  • Temperature Dependence: Like many organic compounds, solubility will generally increase with temperature. Therefore, heating the solvent may result in enhanced solubility for this compound.

To summarize, the solubility of 2-(3-bromo-4-butoxy-phenyl)ethanehydroxamic acid can be described as moderate to high in polar solvents and limited in non-polar solvents, influenced by factors like temperature and pH. This versatile solubility profile makes it a candidate for various applications in chemical research and industry.

Interesting facts

Interesting Facts about 2-(3-bromo-4-butoxy-phenyl)ethanehydroxamic acid

2-(3-bromo-4-butoxy-phenyl)ethanehydroxamic acid is a fascinating compound that has garnered attention due to its unique chemical structure and potential applications. Here are some interesting insights:

  • Structural Intricacies: The compound contains a hydroxamic acid functional group, which is characterized by its ability to form complexes with metal ions, making it particularly valuable in coordination chemistry.
  • Pharmaceutical Potential: With increasing research in medicinal chemistry, compounds similar to this have been evaluated for their anti-cancer and anti-inflammatory properties, highlighting their importance in drug discovery.
  • Bromine Influence: The presence of the bromine atom in the compound suggests that it may exhibit varied reactivity, sometimes enhancing biological activity. Brominated compounds are known for their ability to penetrate biological membranes and may impact the compound's biological efficacy.
  • Butoxy Group: The butoxy substituent contributes to the hydrophobic characteristics of the compound, potentially influencing its interaction with biological systems or enhancing lipophilicity, which is critical in drug formulation.
  • Research Applications: This compound is likely to be of interest in synthetic organic chemistry and may be useful in the development of new materials or in the study of complex organic reactions.

As scientists continue to explore the properties and potential of 2-(3-bromo-4-butoxy-phenyl)ethanehydroxamic acid, it stands as a promising candidate for further investigation in diverse fields, ranging from medicinal chemistry to materials science.

Synonyms
15560-64-2
BRN 2863287
ACETOHYDROXAMIC ACID, 2-(3-BROMO-4-BUTOXYPHENYL)-
2-(3-Bromo-4-butoxyphenyl)acetohydroxamic acid
DTXSID00165926
DTXCID5088417
2-(3-bromo-4-butoxyphenyl)-N-hydroxyacetamide