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Iopamidol

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Identification
Molecular formula
C17H22I3N3O7
CAS number
60166-93-0
IUPAC name
2-[3-(butanoylamino)-2,4,6-triiodo-phenyl]butanoic acid
State
State

At room temperature, Iopamidol is in a solid state. When dissolved in water, it is used as a radiographic contrast medium for various imaging procedures.

Melting point (Celsius)
141.00
Melting point (Kelvin)
414.00
Boiling point (Celsius)
774.00
Boiling point (Kelvin)
1 047.00
General information
Molecular weight
777.09g/mol
Molar mass
777.0860g/mol
Density
1.5000g/cm3
Appearence

Iopamidol is typically a white or almost white crystalline powder. It is soluble in water, forming a clear solution, which is beneficial for its use as a contrast agent in medical imaging.

Comment on solubility

Solubility of 2-[3-(butanoylamino)-2,4,6-triiodo-phenyl]butanoic acid

The solubility of 2-[3-(butanoylamino)-2,4,6-triiodo-phenyl]butanoic acid is influenced by several structural characteristics inherent in its chemical composition. Typically, compounds containing multiple halogen atoms, such as iodine in this case, exhibit unique solubility properties. Here are some aspects to consider:

  • Polar vs Non-Polar: The presence of the butanoylamino group introduces polarity, which can facilitate solubility in polar solvents such as water.
  • Hydrophobic Regions: The butanoic acid moiety may hinder its overall solubility due to its hydrophobic characteristics, potentially leading to lower solubility in aqueous environments.
  • Temperature Effects: Temperature may also play a critical role, as solubility can increase with rising temperatures for many organic compounds.
  • pH Dependence: The solubility may vary with pH, attributed to the carboxylic acid functional group, which can ionize to form a negatively charged species, enhancing water solubility in alkaline conditions.

In conclusion, the solubility of this compound is not straightforward and is subject to variations based on the solvent used, temperature, and pH levels. While it may exhibit some degree of solubility in polar solvents, the presence of both hydrophilic and hydrophobic characteristics suggests that solubility may be moderately limited.

Interesting facts

Interesting Facts about 2-[3-(butanoylamino)-2,4,6-triiodo-phenyl]butanoic acid

2-[3-(butanoylamino)-2,4,6-triiodo-phenyl]butanoic acid is a compound that showcases the fascinating interplay between organic chemistry and medicinal applications. Here are some intriguing aspects:

  • Structural Complexity: This compound features a multifunctional structure combining both aromatic and aliphatic components, which allows for unique biochemical interactions.
  • Biological Relevance: Analogous compounds are often studied for their potential in pharmaceuticals, particularly in the development of treatments for conditions requiring iodine-based agents.
  • Halogen Chemistry: The inclusion of three iodine atoms introduces significant halogen chemistry principles, making it a key subject for research in the fields of medicinal chemistry and toxicology.
  • Potential Applications: Compounds with similar structures are under investigation for their roles in imaging techniques such as PET scans, as the high atomic number of iodine provides distinct imaging capabilities.
  • Research Opportunities: The unique attributes of this compound open doors for further studies on its synthesis and potential modifications to enhance its effectiveness in various applications.

As expressed by many chemists, “the complexity of a molecule often mirrors the complexity of its potential applications.” In the context of 2-[3-(butanoylamino)-2,4,6-triiodo-phenyl]butanoic acid, the intricate design suggests vast possibilities not only in medicinal chemistry but also in the realm of synthetic organic chemistry.

With ongoing research, this compound might play a vital role in pioneering new therapeutic pathways. The journey of understanding compounds like this is where science truly flourishes!

Synonyms
29067-72-9
BRN 3006554
2-(3-Butyramido-2,4,6-triiodophenyl)butyric acid
BUTYRIC ACID, 2-(3-BUTYRAMIDO-2,4,6-TRIIODOPHENYL)-
RefChem:331247
DTXSID70951671
2-{3-[(1-Hydroxybutylidene)amino]-2,4,6-triiodophenyl}butanoic acid