Skip to main content

Iopamidol

ADVERTISEMENT
Identification
Molecular formula
C17H22I3N3O8
CAS number
60166-93-0
IUPAC name
2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methyl]butanoic acid
State
State

At room temperature, Iopamidol is typically provided in an aqueous solution state as it is often used directly as an injectable contrast medium for imaging procedures. In its raw form, it is a solid powder.

Melting point (Celsius)
85.00
Melting point (Kelvin)
358.15
Boiling point (Celsius)
585.70
Boiling point (Kelvin)
858.85
General information
Molecular weight
777.09g/mol
Molar mass
777.0860g/mol
Density
1.4690g/cm3
Appearence

Iopamidol appears as a white crystalline powder that is odorless and tastes slightly bitter. It is often available as a sterile, aqueous solution for medical use, particularly for radiographic imaging. In its solid form, it may form crystals or powder, and in solution, it is clear and colorless.

Comment on solubility

Solubility Properties of 2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methyl]butanoic acid (C17H22I3N3O8)

The solubility of 2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methyl]butanoic acid is influenced by its complex structure, which contains multiple functional groups and several iodine atoms. Understanding solubility requires consideration of various factors:

  • Polarity: The presence of three iodine atoms makes this compound relatively polar, which affects its interaction with various solvents.
  • Hydrophilicity vs. Hydrophobicity: The butanoylamino group may introduce some hydrophilic characteristics, whereas the iodine substituents may contribute to a hydrophobic nature, leading to mixed solubility.
  • Solvent Compatibility: This compound is expected to show different solubility behaviors in organic solvents (e.g., ethanol, acetone) compared to polar solvents (e.g., water).
  • Temperature Influence: Like many organic compounds, solubility may increase with temperature, allowing greater solvent interaction.

In conclusion, while exact solubility data may not be readily available, it is reasonable to infer that the solubility of this compound will be moderate in organic solvents but may face challenges when interacting with aqueous environments due to the competing influences of its polar and nonpolar characteristics. Further experimental investigation would provide clearer insights into its solubility profile.

Interesting facts

Interesting Facts about 2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methyl]butanoic acid

2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methyl]butanoic acid, a fascinating compound in the realm of medicinal chemistry, especially stands out due to its unique structure and potential applications. Here are some intriguing aspects:

  • Complex Structure: This compound features a triiodinated phenyl group, which introduces notable physical and chemical properties. The presence of iodine enhances the compound's utility in various imaging techniques, such as positron emission tomography (PET).
  • Biological Significance: Compounds similar to this have been studied for their potential uses in targeted therapies, particularly in cancer treatment. The amino and butanoic acid functionalities play critical roles in interacting with biological systems.
  • Versatile Applications: Due to its structural versatility, this compound could be considered in drug design, acting as a scaffold for creating analogs with improved efficacy or reduced toxicity.
  • Research Potential: Scientists are keen to explore analogues of this compound to uncover new medicinal properties, enhancing its overall therapeutic index.

The intricate nature of 2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methyl]butanoic acid not only makes it a subject of academic interest but also highlights the intersection of chemistry and medicine. As research progresses, who knows what new discoveries will unfold?

Synonyms
Tyropanoic acid
TYROPANIC ACID
27293-82-9
tyropanoate
Acidum tyropanoicum
4F05V145YR
EINECS 248-389-8
2-[[3-(butanoylamino)-2,4,6-triiodophenyl]methyl]butanoic acid
DTXSID5048269
2-[3-(BUTYRYLAMINO)-2,4,6-TRIIODOBENZYL]BUTYRIC ACID
TYROPANOIC ACID [WHO-DD]
Bilopac
Bilopaque
Lumopaque
Tyropaque
2-(3-(Butyrylamino)-2,4,6-triiodobenzyl)butanoic acid
Benzenepropanoic acid, a-ethyl-2,4,6-triiodo-3-[(1-oxobutyl)amino]-
2-(3-Butyramido-2,4,6-triiodobenzyl)butanoic acid
2-[(3-butanamido-2,4,6-triiodophenyl)methyl]butanoic acid
Tyropanoic acid sodium salt
NSC107434
2-(3-(Butyrylamino)-2,4,6-triiodobenzyl)butyric acid
2-((3-butanamido-2,4,6-triiodophenyl)methyl)butanoic acid
UNII-4F05V145YR
starbld0000838
Tyropanoate sodium(USAN
TYROPANOATE [VANDF]
Sodium Tyropanoate (USAN)
SCHEMBL2788021
CHEMBL1201261
DTXCID0028244
CHEBI:135862
YMOXVLQZFAUUKI-UHFFFAOYSA-N
DB09340
DB-251117
NS00028280
EN300-18568448
Q6587055
Hydrocinnamic acid, 3-butyramido-.alpha.-ethyl-2,4,6-triiodo-
Sodium 3-butyramido-.alpha.-ethyl-2,4,6-triiodohydrocinnamate
2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methyl]butanoic acid
Benzenepropanoic acid, alpha-ethyl-2,4,6-triiodo-3-((1-oxobutyl)amino)-
Hydrocinnamic acid, 3-butyramido-.alpha.-ethyl-2,4,6-triiodo-, sodium salt
BENZENEPROPANOIC ACID, .ALPHA.-ETHYL-2,4,6-TRIIODO-3-((1-OXOBUTYL)AMINO)-
Hydrocinnamic acid, 3-butyramido-.alpha.-ethyl-2,4, 6-triiodo-, monosodium salt
Benzenepropanoic acid, .alpha.-ethyl-2,4, {6-triiodo-3-[(1-oxobutyl)amino]-,} monosodium salt