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Iodipamide

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Identification
Molecular formula
C20H18I3NO4
CAS number
54-64-8
IUPAC name
2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methylene]butanoic acid
State
State

At room temperature, iodipamide is typically encountered as a solid. Due to its application in medical imaging, it is often used in solution form which remains clear and stable under normal storage conditions.

Melting point (Celsius)
211.00
Melting point (Kelvin)
484.15
Boiling point (Celsius)
254.20
Boiling point (Kelvin)
527.35
General information
Molecular weight
667.87g/mol
Molar mass
667.8480g/mol
Density
1.9500g/cm3
Appearence

Iodipamide appears as a white to off-white crystalline powder. It is often encountered as its meglumine salt form in radiographic imaging applications. The crystals can vary slightly in color due to impurities or hydration states.

Comment on solubility

Solubility of 2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methylene]butanoic acid

The solubility of 2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methylene]butanoic acid is influenced by several factors, including its specific functional groups and structural characteristics.

  • Polar versus Nonpolar Character: The presence of butanoylamino and triiodophenyl groups suggests a degree of polar character which may enhance solubility in polar solvents.
  • Influence of Hydrogen Bonding: The carboxylic acid functional group may engage in hydrogen bonding, further enhancing solubility in polar environments, such as water.
  • Halogen Atoms: The presence of iodine atoms can introduce significant van der Waals forces, potentially affecting solubility in nonpolar solvents.

In summary, the solubility of this compound can be predicted to be:

  1. Higher in polar solvents like water due to hydrogen bonding and polar interactions.
  2. Lower in nonpolar solvents because of the bulky structure and potential aggregation of triiodo substituents.
  3. Dependent on temperature, with increased temperatures often leading to increased solubility.

Ultimately, empirical data would be essential for precise solubility measurements, but the theoretical considerations provide a foundational understanding of its solubility behavior.

Interesting facts

Interesting Facts about 2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methylene]butanoic acid

This unique compound, 2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methylene]butanoic acid, has garnered attention in both research and medicinal chemistry due to its intricate structure and potential applications. Here are some noteworthy points that highlight its significance:

  • Structural Complexity: The presence of the tri-iodo group in the phenyl ring signifies a remarkable degree of halogenation, which can influence the compound's reactivity and functionality.
  • Biological Relevance: Compounds with similar structures are often evaluated for their biological activities, especially in the field of drug discovery. The butanoylamino moiety suggests potential interactions in biological systems.
  • Potential Applications: While still under research, this compound could find uses in areas such as:
    • Pharmaceutical developments
    • Diagnostic imaging (due to the iodine isotopes)
    • Agricultural chemistry as a possible agrochemical agent
  • Research Interest: The incorporation of iodine often leads to unique properties such as increased lipophilicity and structural stability, making such compounds intriguing for studies in both synthetic and medicinal chemistry.
  • Environmental Impact: It's crucial to investigate the ecological implications of such halogenated compounds, as iodine can potentially contribute to bioaccumulation.

As research progresses, the insights gained from studying compounds like 2-[[3-(butanoylamino)-2,4,6-triiodo-phenyl]methylene]butanoic acid can provide invaluable information for both theoretical chemistry and practical applications.

In the words of a notable chemist, "Every compound holds a story waiting to be unraveled through the lens of scientific inquiry."

Synonyms
IX9VVF69JR
SCHEMBL11300036
DTXSID20862607
2-[(3-BUTANAMIDO-2,4,6-TRIIODOPHENYL)METHYLIDENE]BUTANOIC ACID
2-[[3-(butanoylamino)-2,4,6-triiodophenyl]methylidene]butanoic acid