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Iohexol

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Identification
Molecular formula
C19H26I3N3O9
CAS number
66108-95-0
IUPAC name
2-[3-[butanoyl(ethyl)amino]-2,4,6-triiodo-phenoxy]butanoic acid
State
State

Iohexol is typically encountered as a solid at room temperature. In medical settings, it is commonly used in a liquid solution form as an injectable medium for radiographic imaging.

Melting point (Celsius)
182.00
Melting point (Kelvin)
455.15
Boiling point (Celsius)
330.00
Boiling point (Kelvin)
603.15
General information
Molecular weight
821.14g/mol
Molar mass
821.1390g/mol
Density
1.4004g/cm3
Appearence

Iohexol appears as a white crystalline powder. It is often used in a solution form for medical imaging purposes. As a raw compound, it is typically odorless and has a high refractive index compared to water, which aids its function in enhancing imaging contrast.

Comment on solubility

Solubility of 2-[3-[butanoyl(ethyl)amino]-2,4,6-triiodo-phenoxy]butanoic acid

Understanding the solubility of the compound 2-[3-[butanoyl(ethyl)amino]-2,4,6-triiodo-phenoxy]butanoic acid is essential for its applications in various fields. Here are some key points regarding its solubility:

  • Polarity: The presence of multiple polar functional groups suggests that the compound may exhibit some level of hydrophilicity, potentially enhancing its solubility in polar solvents such as water.
  • Hydrophobic Regions: The butanoyl(ethyl)amino portion introduces a hydrophobic character, which might limit solubility in aqueous environments but could enhance solubility in organic solvents.
  • Temperature Sensitivity: Like many organic compounds, its solubility may increase with temperature, which is an important factor to consider in application scenarios.
  • pH Dependency: The carboxylic acid functional group implies that solubility could be pH-dependent, with higher solubility expected in basic conditions due to deprotonation.

In summary, the solubility of 2-[3-[butanoyl(ethyl)amino]-2,4,6-triiodo-phenoxy]butanoic acid is influenced by a balance of its polar and non-polar characteristics, while factors like temperature and pH play crucial roles in determining its overall solubility profile.

Interesting facts

Exploring 2-[3-[butanoyl(ethyl)amino]-2,4,6-triiodo-phenoxy]butanoic Acid

2-[3-[butanoyl(ethyl)amino]-2,4,6-triiodo-phenoxy]butanoic acid is a fascinating compound that catches the attention of chemists for several reasons. Here, we delve into its notable aspects:

Chemical Composition and Structure

This compound demonstrates a complex structure, characterized by its numerous functional groups and the presence of iodine atoms. The key features include:

  • Triiodo-phenoxy moiety: This part indicates that the compound incorporates three iodine atoms on a phenol ring, which is known for enhancing biological activity.
  • Butanoyl(ethyl)amino group: The presence of this group indicates potential for various interactions, particularly in biochemical settings.

Implications in Research

Due to its unique structural features, this compound has various implications in research, including:

  • Pharmaceutical applications: Molecules with iodine substitutions are often used in drug development due to their influence on biological activity.
  • Diagnostics: The triiodinated structure may offer utility in imaging applications, particularly in radiology and diagnostic screenings.

Biological Activity

Compounds like 2-[3-[butanoyl(ethyl)amino]-2,4,6-triiodo-phenoxy]butanoic acid are significant in the field of medicinal chemistry. They can:

  • Engage in various biological interactions, potentially acting as enzyme inhibitors.
  • Exhibit anti-inflammatory or antimicrobial properties, making them of interest for further study.

As you delve into the chemical world, remember how compounds like this play a critical role in advancing our understanding of chemistry and medicine! Their intricate designs lead to innovative solutions in diverse scientific fields.


Synonyms
24340-26-9
BRN 2677769
2-(3-(N-Ethylbutyramido)-2,4,6-triiodophenoxy)butyric acid
BUTYRIC ACID, 2-(3-(N-ETHYLBUTYRAMIDO)-2,4,6-TRIIODOPHENOXY)-
RefChem:331240
DTXSID00947183
2-{3-[Butanoyl(ethyl)amino]-2,4,6-triiodophenoxy}butanoic acid