Skip to main content

Iohexol

ADVERTISEMENT
Identification
Molecular formula
C19H26I3N3O9
CAS number
66108-95-0
IUPAC name
2-[3-[butanoyl(ethyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid
State
State

At room temperature, iohexol is typically encountered as a solid. It is used in an aqueous solution for medical applications, particularly in imaging diagnostics. As a solid, it is stable and does not readily volatilize.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.00
Boiling point (Celsius)
670.00
Boiling point (Kelvin)
943.00
General information
Molecular weight
821.14g/mol
Molar mass
821.1400g/mol
Density
1.4410g/cm3
Appearence

Iohexol appears as a white to off-white crystalline powder. It is typically odorless and is soluble in water, which allows it to be used effectively in various medical imaging procedures. Under light, it may have a faint sheen, and when viewed under a microscope, the individual crystal formations can be observed.

Comment on solubility

Solubility of 2-[3-[butanoyl(ethyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid

When examining the solubility of 2-[3-[butanoyl(ethyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid, several factors are crucial to consider:

  • Polarity: This compound contains both polar and non-polar functional groups. The presence of the hexanoic acid moiety suggests some level of acidity and polarity, which might enhance solubility in polar solvents such as water.
  • Iodine Substitution: The three iodine atoms substituted on the aromatic ring could significantly influence its overall solubility. Generally, halogenated compounds tend to exhibit unique solubility profiles due to steric hindrance and increased molecular weight.
  • Amine Functionality: The butanoyl(ethyl)amino group could contribute to hydrogen bonding with solvents, potentially enhancing solubility in polar environments.
  • Environmental Conditions: Solubility can vary with temperature and pH levels. It's essential to assess how these conditions may change the solubility of this compound.

In summary, the solubility of this complex compound is likely to be influenced by a blend of polar and non-polar characteristics, making it more soluble in organic solvents compared to aqueous ones. As with many organic compounds, empirical studies are essential to establish precise solubility parameters.

Interesting facts

Interesting Facts about 2-[3-[Butanoyl(ethyl)amino]-2,4,6-triiodo-phenoxy]hexanoic Acid

2-[3-[Butanoyl(ethyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid is a fascinating compound, notable for its complex structure and potential applications in chemical science. Here are some interesting insights:

  • Structural Complexity: This compound features a unique arrangement, including multiple functional groups that confer distinct chemical properties and biological activity.
  • Halogen Influence: The presence of iodine atoms in its structure significantly enhances the compound's reactivity and stability, making it a subject of interest in medicinal chemistry.
  • Pharmacological Potential: Compounds with halogenated aromatic rings often exhibit potent biological activities, including antimicrobial and anti-inflammatory properties.
  • Versatile Applications: This compound could be useful in drug design, especially in the development of targeted therapies due to its ability to interact with specific biological macromolecules.
  • Environmental Relevance: Understanding the degradation and persistence of triiodinated compounds in the environment can provide insights into their ecological impacts and help in designing safer alternatives.

As a chemistry student or a scientist exploring this compound, you might find it enlightening to consider its role in advancing both synthetic methodologies and biological research. Its multifaceted characteristics not only open doors to innovative applications but also raise questions about its environmental fate, making it a worthier subject of study.

"In chemistry, every compound tells a story; let's unravel the tales of complexity and innovation with 2-[3-[Butanoyl(ethyl)amino]-2,4,6-triiodo-phenoxy]hexanoic acid."

Synonyms
22275-42-9
BRN 2679184
2-(3-(N-Ethylbutyramido)-2,4,6-triiodophenoxy)hexanoic acid
HEXANOIC ACID, 2-(3-(N-ETHYLBUTYRAMIDO)-2,4,6-TRIIODOPHENOXY)-
RefChem:347661
DTXSID20944937
2-[[3-(N-Ethylbutanoylamino)-2,4,6-triiodophenyl]oxy]hexanoic acid
2-{3-[butanoyl(ethyl)amino]-2,4,6-triiodophenoxy}hexanoic acid