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Clomipramine

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Identification
Molecular formula
C19H23ClN2O
CAS number
303-49-1
IUPAC name
2-[(3-chloro-1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2(7),3,5,9,11,13-hexaenyl)oxy]-N,N-dimethyl-ethanamine
State
State

Clomipramine is primarily a solid at room temperature under standard conditions.

Melting point (Celsius)
190.50
Melting point (Kelvin)
463.60
Boiling point (Celsius)
525.50
Boiling point (Kelvin)
798.70
General information
Molecular weight
314.86g/mol
Molar mass
314.8360g/mol
Density
1.1800g/cm3
Appearence

Clomipramine appears as a white or slightly yellow crystalline powder. It is typically odorless and has a bitter taste.

Comment on solubility

Solubility Characteristics

The solubility of the compound 2-[(3-chloro-1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2(7),3,5,9,11,13-hexaenyl)oxy]-N,N-dimethyl-ethanamine can be quite complex due to its unique molecular structure. Several factors influence its solubility:

  • Polarity: The presence of polar functional groups often enhances water solubility, while hydrophobic regions can lead to decreased solubility.
  • Molecular Size: Larger and more complex molecules typically exhibit lower solubility in polar solvents due to steric hindrance.
  • Temperature: Increased temperature generally increases solubility for most compounds, but the specific behavior can vary based on intermolecular interactions.
  • Solvent Interactions: Solubility is highly dependent on the type of solvent used—non-polar solvents may dissolve hydrophobic parts while polar solvents may interact with the more polar facets.

As a result, one might observe the following:

  • If tested in water, this compound may demonstrate limited solubility due to the extensive hydrophobic character.
  • When placed in non-polar solvents such as hexane or chloroform, it may exhibit significantly higher solubility, underlining the importance of solvent choice.
  • Overall, it is crucial to consider these properties when predicting the solubility behavior of this compound in various environments.

In summary, understanding the solubility of this unique compound requires careful examination of its chemical structure and the nature of the solvent. As the saying goes, "Like dissolves like," emphasizing the need to match polarities for optimal solubility.

Interesting facts

Interesting Facts about 2-[(3-chloro-1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2(7),3,5,9,11,13-hexaenyl)oxy]-N,N-dimethyl-ethanamine

This fascinating compound belongs to a class of chemicals that exhibit a highly complex structure, characterized by its intricate tetracyclic framework. Such structures often hold significant potential in medicinal chemistry due to their unique stereochemistry and the ability to interact with biological targets in distinctive ways.

Applications and Significance

The compound has drawn attention in several fields, including:

  • Pharmaceutical Development: Compounds with similar frameworks are often evaluated for their therapeutic properties, especially in cancer research and targeting specific malignancies.
  • Study of Molecular Interactions: The multiple rings in the structure allow scientists to explore complex interactions with enzymes and receptors, shedding light on biological processes.
  • Unique Mechanisms of Action: Such compounds may operate through novel pathways, offering insights into diverse biological mechanisms and potential new treatment strategies.

Chemical Characteristics

The 3-chloro substitution on the heterocyclic system is pivotal. Here are key points about this feature:

  • Reactivity: The chlorine atom can influence the reactivity and stability of the compound, making it an interesting subject for further studies in chemical synthesis.
  • Biological Activity: Halogenated compounds are often noted for increased biological activity, which is of significant interest in drug design.

Research and Development

Given the complexity and potential applications, ongoing research might focus on:

  • Synthetic Pathways: Developing more efficient synthetic routes to create this compound and its analogs.
  • Biological Testing: Evaluating the compound’s efficacy and safety in various biological systems.
  • Structure-Activity Relationships (SAR): Understanding how modifications to the structure can enhance its therapeutic effects.

In conclusion, this compound serves as an excellent example of the intricate relationship between chemical structure and biological function, promising exciting opportunities for future research in various scientific domains.