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Clonazepam

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Identification
Molecular formula
C15H10ClN3O3
CAS number
1622-61-3
IUPAC name
2-(3-chloro-11-methyl-6-oxo-benzo[b][1,4]benzodiazepin-5-yl)ethyl-dimethyl-ammonium;chloride
State
State

Clonazepam is generally available as a solid at room temperature, often formulated into tablets or powder.

Melting point (Celsius)
235.00
Melting point (Kelvin)
508.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
315.72g/mol
Molar mass
315.7150g/mol
Density
1.5000g/cm3
Appearence

Clonazepam is typically a white to pale yellow crystalline powder. It is almost odorless and tasteless.

Comment on solubility

Solubility of 2-(3-chloro-11-methyl-6-oxo-benzo[b][1,4]benzodiazepin-5-yl)ethyl-dimethyl-ammonium; chloride

The solubility of the compound 2-(3-chloro-11-methyl-6-oxo-benzo[b][1,4]benzodiazepin-5-yl)ethyl-dimethyl-ammonium; chloride can be influenced by several factors due to its complex molecular structure. Here are some key points regarding its solubility:

  • Solvent Dependency: This compound is expected to exhibit varying solubility in different solvents. It may demonstrate higher solubility in polar solvents such as water, given the presence of the quaternary ammonium group, which generally enhances water solubility.
  • pH Influence: The solubility could be pH-dependent. In acidic conditions, the presence of chloride ions from the ammonium salt may create a more soluble ionic form.
  • Temperature Effects: Increasing temperature often leads to increased solubility for many organic compounds; thus, heating the solvent may enhance the solubility of this compound.
  • Interactions with Other Compounds: Interactions with other solutes or potential surfactants can also alter solubility characteristics, making it essential to consider the overall environment.

As a general point, it can be stated that “the solubility of organic compounds often hinges on the interplay between their molecular structure and the properties of the solvent.” Thus, careful experimentation is recommended to determine the precise solubility profile for this specific compound in various solvents. Further investigation is crucial to fully understand its behavior in solution.

Interesting facts

Interesting Facts about 2-(3-chloro-11-methyl-6-oxo-benzo[b][1,4]benzodiazepin-5-yl)ethyl-dimethyl-ammonium;chloride

The compound known as 2-(3-chloro-11-methyl-6-oxo-benzo[b][1,4]benzodiazepin-5-yl)ethyl-dimethyl-ammonium; chloride is a fascinating example of a *benzodiazepine derivative*. Here are some key points regarding this intriguing compound:

  • Pharmacological Significance: Benzodiazepines are widely recognized for their anxiolytic, sedative, and anticonvulsant properties. This compound's unique structure potentially enhances its efficacy and specificity in these therapeutic areas.
  • Structure-Activity Relationship (SAR): The presence of the chloro group and the oxo function at strategic positions within the *benzodiazepine core* may influence the compound’s interaction with the GABAA receptors, enhancing its pharmacological activity.
  • Research Applications: Due to its complex structure, this compound may serve as a valuable tool in neurological studies and drug development, particularly in exploring new anxiolytics with reduced side effects.
  • Quaternary Ammonium Component: The inclusion of a dimethylammonium moiety significantly alters the compound's lipophilicity and may play a role in its ability to cross biological membranes, making it essential for bioactivity.

Furthermore, the compound can be utilized in the development of targeted drug delivery systems, which aim to improve the therapeutic window of benzodiazepines, mitigating the risks associated with their use.

As a scientist or a chemistry student, understanding the nuances of such compounds can pave the way for innovative drug design and therapeutic advancements. Thus, the study of 2-(3-chloro-11-methyl-6-oxo-benzo[b][1,4]benzodiazepin-5-yl)ethyl-dimethyl-ammonium; chloride is not just an exploration of chemical composition, but a journey into enhancing human health and well-being.

Synonyms
15496-52-3
5H-Dibenzo(b,e)(1,4)diazepin-11-one, 10,11-dihydro-8-chloro-10-(2-(dimethylamino)ethyl)-5-methyl-, hydrochloride