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2-(3-chloro-4-pentoxyphenyl)ethanehydroxamic acid

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Identification
Molecular formula
C13H18ClNO3
CAS number
421-38-5
IUPAC name
2-(3-chloro-4-pentoxy-phenyl)ethanehydroxamic acid
State
State

At room temperature, 2-(3-chloro-4-pentoxyphenyl)ethanehydroxamic acid is in a solid state, typically crystalline in nature.

Melting point (Celsius)
102.50
Melting point (Kelvin)
375.65
Boiling point (Celsius)
345.20
Boiling point (Kelvin)
618.35
General information
Molecular weight
263.74g/mol
Molar mass
263.7280g/mol
Density
1.1790g/cm3
Appearence

The compound appears as a crystalline solid under typical conditions.

Comment on solubility

Solubility of 2-(3-chloro-4-pentoxy-phenyl)ethanehydroxamic acid

The solubility of 2-(3-chloro-4-pentoxy-phenyl)ethanehydroxamic acid can be characterized by several key factors:

  • Polarity: This compound exhibits varying polarity due to the presence of both hydroxamic acid and alkoxy functional groups. Generally, hydroxamic acids tend to have decent solubility in polar solvents like water, yet the alkoxy group might influence its overall solubility.
  • Solvent Compatibility: It is likely to be more soluble in organic solvents such as methanol, ethanol, and acetone compared to water. This is primarily due to the hydrophobic pentoxy group which can hinder solubility in highly polar environments.
  • pH Dependence: The solubility of hydroxamic acids can also depend significantly on pH. At different pH levels, the protonation state of the functional groups alters, potentially enhancing solubility in different solvents.

In summary, while 2-(3-chloro-4-pentoxy-phenyl)ethanehydroxamic acid shows some **solubility in polar solvents**, there are many complexities involved. Its **versatile nature** allows it to interact with both aqueous and organic solvents, making it an interesting compound for further solubility studies.

Interesting facts

Interesting Facts about 2-(3-Chloro-4-pentoxy-phenyl)ethanehydroxamic acid

2-(3-Chloro-4-pentoxy-phenyl)ethanehydroxamic acid, often referred to in research as a hydroxamic acid derivative, exhibits unique properties and potential applications that capture the interest of chemists and students alike. Below are some of the noteworthy aspects of this intriguing compound:

  • Functional Group Chemistry: Hydroxamic acids are notable for featuring an –OH (hydroxyl) group attached to an amide. This structure often endows the compound with diverse reactivity, making it essential in many organic transformations.
  • Inhibitory Potential: Many hydroxamic acids, including this compound, are known for their ability to inhibit metalloproteinases, which play key roles in various biological processes. This highlights their potential in therapeutic applications, particularly in the context of cancer and other diseases.
  • Research Applications: Due to its unique structure, this specific hydroxamic acid derivative may be a subject of research in medicinal chemistry, enabling the development of new drugs or treatments. Its properties lend themselves to investigations into structure-activity relationships.
  • Environmental Implications: Compounds like this can be studied for their roles in agricultural chemistry, potentially acting as herbicides or pesticides due to their ability to interact with biological systems.
  • Synthetic Versatility: The presence of both a chloro and a pentoxy group suggests multiple pathways for further functionalization, making it a valuable intermediate in organic synthesis.

As Chemists, we find that every compound tells a story. The research surrounding 2-(3-Chloro-4-pentoxy-phenyl)ethanehydroxamic acid illustrates the dynamic interplay between structure and function in the realm of organic chemistry. Scientists are continually exploring the implications of such compounds, paving the way for advancements in both medical and environmental fields.

Synonyms
23142-41-8
2-(3-Chloro-4-pentyloxy)phenylacetohydroxamic acid
ACETOHYDROXAMIC ACID, 2-(3-CHLORO-4-PENTYLOXY)PHENYL-
RefChem:316779
2-(3-chloro-4-pentoxyphenyl)-N-hydroxyacetamide
DTXSID10945817
2-[3-Chloro-4-(pentyloxy)phenyl]-N-hydroxyethanimidic acid