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N-Chloroacetyl amino acid

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Identification
Molecular formula
C9H8ClNO3
CAS number
74431-30-6
IUPAC name
2-[(3-chlorobenzoyl)amino]acetic acid
State
State

At room temperature, this compound is in a solid state, appearing as a crystalline powder.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
510.00
Boiling point (Kelvin)
783.15
General information
Molecular weight
213.61g/mol
Molar mass
213.6110g/mol
Density
1.4674g/cm3
Appearence

This compound typically appears as a white to off-white crystalline powder. It is not known to have any distinctive odor and is stable under standard conditions.

Comment on solubility

Solubility of 2-[(3-chlorobenzoyl)amino]acetic acid (C9H8ClNO3)

The solubility of 2-[(3-chlorobenzoyl)amino]acetic acid is a crucial aspect to consider for its practical applications in synthesis and formulation. This compound, which features both amino and carboxylic acid functional groups, tends to exhibit interesting solubility characteristics.

General Solubility Profile:

  • Water Solubility: Generally, the presence of a carboxylic acid group can enhance solubility in polar solvents like water, particularly in acidic conditions.
  • Organic Solvents: The aromatic chlorobenzoyl portion may confer solubility in organic solvents such as ethanol and methanol, making it versatile for various applications.
  • pH Dependence: The solubility is also influenced by pH, where an increase in acidity may lead to better solvation due to protonation of the amino group.

In summary, the solubility of 2-[(3-chlorobenzoyl)amino]acetic acid can be described as follows:

  1. In polar solvents, it is likely to be relatively soluble.
  2. In nonpolar or less polar solvents, the solubility may decrease.
  3. Its solubility is affected by the surrounding pH, showcasing the importance of environmental conditions.

Understanding the solubility of this compound not only aids in its characterization but also plays a vital role in its potential uses in pharmaceutical applications and chemical synthesis. Always consider solubility parameters when working with this compound to optimize results!

Interesting facts

Interesting Facts About 2-[(3-Chlorobenzoyl)amino]acetic Acid

2-[(3-Chlorobenzoyl)amino]acetic acid is a fascinating compound in the realm of organic chemistry, particularly due to its unique structural features and potential applications. Here are some intriguing elements associated with this compound:

  • Biological Activity: The compound is notable for its biological properties, often studied for its activity against various pharmaceutical targets. The presence of the chlorobenzoyl group may contribute to its ability to interact with specific receptors in biological systems.
  • Applications in Drug Development: Given its structure, this compound has potential implications in the development of new drug candidates. Researchers are continuously exploring how derivatives of 2-[(3-chlorobenzoyl)amino]acetic acid can lead to novel therapeutic agents.
  • Structure-Activity Relationship (SAR): The relationship between the compound’s structure and its biological effects can provide valuable insights. Understanding how modifications to either the chlorobenzoyl or amino groups influence activity is a key area of research.
  • Versatile Synthetic Pathways: The synthesis of this compound can involve various methodologies, showcasing the versatility of organic reactions such as acylation and amination, making it an interesting target for synthetic chemists.
  • Cross-Disciplinary Interest: This compound's relevance spans across chemistry, biology, and pharmacology, making it an appealing topic for interdisciplinary studies and discussions within academic environments.

As a chemistry student or a researcher, exploring compounds like 2-[(3-chlorobenzoyl)amino]acetic acid not only enhances your understanding of organic reactions but also invites appreciation for the intersection of chemistry and potential therapeutic advancements. Always remember the quote:

"Chemistry is the beat of the universe." - Unknown

Embracing compounds like this can be both a scientific challenge and a journey towards innovative solutions in medicine and beyond.

Synonyms
57728-59-3
(3-Chloro-benzoylamino)-acetic acid
m-chlorohippuric acid
2-[(3-chlorobenzoyl)amino]acetic acid
2-(3-Chlorobenzamido)acetic acid
n-(3-chlorobenzoyl)glycine
m-Chloro Hippuric Acid
2-[(3-chlorophenyl)formamido]acetic acid
3-Chlorohippuric acid
(3-Chlorobenzoylamino)acetic acid
[(3-Chlorobenzoyl)amino]acetic acid
Glycine, N-(3-chlorobenzoyl)-
(3-chloro-benzoylamino)acetic acid
NSC-201882
m-chlorohippurate
2-((3-chlorophenyl)formamido)acetic acid
m-Chlorhippursaure
(3-Chlorobenzoylamino)acetic Acid; N-(3-Chlorobenzoyl)glycine; NSC 201882; m-Chlorohippuric Acid; N-(3-Chlorobenzoyl)glycine
MFCD00662251
m-Chloro-hippuric acid
MX3MEQ6BUN
Oprea1_470042
Oprea1_859855
CHEMBL458724
SCHEMBL2984329
2-(3-Chlorobenzamido)aceticacid
DTXSID10274270
CHEBI:176504
ICYUIIJXZHPESK-UHFFFAOYSA-N
HCA72859
N-[(3-chlorophenyl)carbonyl]glycine
NSC201882
STL483032
AKOS000114577
CCG-252281
NSC 201882
CS-0197301
EN300-00155
6E-925
E73994
2-((3-CHLOROPHENYL)CARBONYLAMINO)ETHANOIC ACID
Z56827660
2-[(3-ChlorobenZoyl)amino]acetic acid (BZ(3-Cl)-Gly-OH)
844-260-0