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Clenbuterol

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Identification
Molecular formula
C18H20ClNO
CAS number
355-25-9
IUPAC name
2-(3-chlorophenyl)-1-phenyl-1-(2-pyridyl)propan-2-ol
State
State

At room temperature, this compound is typically in a solid state, commonly found as a powder, especially in the form of its hydrochloride salt.

Melting point (Celsius)
174.50
Melting point (Kelvin)
447.65
Boiling point (Celsius)
366.70
Boiling point (Kelvin)
639.85
General information
Molecular weight
277.78g/mol
Molar mass
277.7840g/mol
Density
1.2800g/cm3
Appearence

This compound appears as a white or almost white crystalline powder. It is often utilized in its hydrochloride salt form which shares a similar appearance.

Comment on solubility

Solubility of 2-(3-chlorophenyl)-1-phenyl-1-(2-pyridyl)propan-2-ol

The solubility of 2-(3-chlorophenyl)-1-phenyl-1-(2-pyridyl)propan-2-ol can be influenced by its structural complexity and polar/non-polar characteristics. Here's an overview of its solubility behavior:

  • Polarity: Due to the presence of multiple aromatic rings and a hydroxyl group, this compound displays polar characteristics, which generally promotes solubility in polar solvents.
  • Solvent Interaction: It is likely to be soluble in ethanol and water to some extent, due to the hydroxyl (-OH) group, which can engage in hydrogen bonding.
  • Non-Polar Solvents: In contrast, solubility in non-polar solvents like hexane may be limited due to the compound's relatively high molecular weight and dipole moment.
  • Temperature Effect: As with many organic compounds, solubility may increase with temperature, leading to enhanced dissolution in polar solvents at elevated temperatures.

In practice, it would be ideal to experiment with various solvents to determine the precise solubility of this compound, as the intermolecular forces play a critical role. The expression that "like dissolves like" holds very much true in understanding the solubility profile of complex molecules like this one.

Interesting facts

Interesting Facts about 2-(3-chlorophenyl)-1-phenyl-1-(2-pyridyl)propan-2-ol

This compound represents a fascinating intersection of organic chemistry and pharmacology, exhibiting unique structural characteristics that underscore its potential applications in medicinal chemistry. As a member of the class of compounds known as chiral alcohols, its stereochemistry may play a vital role in determining its biological activity. Here are some notable aspects:

  • Complex Structure: The compound features multiple functional groups, including a chlorophenyl group and a pyridyl moiety, which contribute to its chemical reactivity and interactions with biological targets.
  • Potential Biological Activity: Compounds like this one may serve as ligands in medicinal chemistry. Their ability to interact with specific receptors in the body makes them candidates for further research in the development of therapeutics.
  • Synthesis and Optimization: The synthesis of such compounds often involves multi-step reactions, offering opportunities to explore various synthetic pathways. Optimization of these pathways is crucial for improving yield and efficiency.
  • Chirality Matters: The chirality of this compound could have significant implications for its pharmacological effects, as different enantiomers can exhibit wildly different biological activities.
  • Environmental Research: Investigating the environmental impact of such compounds is essential, considering how they may behave and degrade in natural ecosystems.

As chemists delve deeper into the functionalities of 2-(3-chlorophenyl)-1-phenyl-1-(2-pyridyl)propan-2-ol, the integration of synthetic chemistry and biological applications continues to reveal promising avenues for research and development.

Synonyms
13997-39-2
1-(3-Chlorophenyl)-1-methyl-2-phenyl-2-(2-pyridine)ethanol
RefChem:74298
2-(3-chlorophenyl)-1-phenyl-1-pyridin-2-ylpropan-2-ol
NSC-174273
NSC174272
NSC 174273
CHEMBL3248599
DTXSID20930678
NSC174273
2-Pyridineethanol, .alpha.-(3-chlorophenyl)-.alpha.-methyl-.beta.-phenyl-
NSC-174272
DS-004456
2-Pyridineethanol, a-(3-chlorophenyl)-a-methyl-b-phenyl-
2-(3-CHLOROPHENYL)-1-PHENYL-1-(PYRIDIN-2-YL)PROPAN-2-OL
2-Pyridineethanol, alpha-(3-chlorophenyl)-alpha-methyl-beta-phenyl-