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3-Chloro-2,3-dimethyl-2-phenylbutane-1,3-diol

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Identification
Molecular formula
C11H15ClO2
CAS number
74735-48-7
IUPAC name
2-(3-chlorophenyl)-3-methyl-butane-2,3-diol
State
State

At room temperature, 3-chloro-2,3-dimethyl-2-phenylbutane-1,3-diol is typically found in a solid-state, appearing as a crystalline powder.

Melting point (Celsius)
103.50
Melting point (Kelvin)
376.70
Boiling point (Celsius)
298.80
Boiling point (Kelvin)
572.00
General information
Molecular weight
216.69g/mol
Molar mass
216.6910g/mol
Density
1.1830g/cm3
Appearence

This compound typically appears as a white to off-white crystalline powder. It may form clear crystals under certain conditions.

Comment on solubility

Solubility of 2-(3-chlorophenyl)-3-methyl-butane-2,3-diol

2-(3-chlorophenyl)-3-methyl-butane-2,3-diol, a compound with significant structural complexity, exhibits unique solubility characteristics. Understanding the solubility profile of this compound can be crucial in various applications such as pharmaceuticals and organic synthesis.

Factors Influencing Solubility

The solubility of this compound can be influenced by several factors:

  • Polarity: The presence of hydroxyl (-OH) groups typically increases polarity, enhancing solubility in polar solvents such as water.
  • Hydrogen bonding: The -OH groups can engage in hydrogen bonding, which can further facilitate its interaction with water molecules.
  • Substituent effects: The 3-chlorophenyl group adds a degree of hydrophobicity, which may limit solubility in purely aqueous environments.

Solubility Profile

Reports on the solubility of this compound suggest that:

  • It is moderately soluble in water due to its dual nature of being polar and non-polar.
  • The solubility may increase in polar organic solvents, such as ethanol or methanol.
  • Conversely, it is likely to be less soluble in non-polar solvents, where the hydrophobic characteristics of the chlorophenyl group dominate.

In summary, the solubility of 2-(3-chlorophenyl)-3-methyl-butane-2,3-diol reflects a balance between its polar and non-polar features. As a result, it provides interesting opportunities for targeted solubility modifications in various chemical environments.

Interesting facts

Interesting Facts about 2-(3-Chlorophenyl)-3-methyl-butane-2,3-diol

2-(3-Chlorophenyl)-3-methyl-butane-2,3-diol is a fascinating chemical compound with unique properties and potential applications. Here are some intriguing aspects to consider:

  • Synthetic Origins: This compound belongs to a class of organic molecules known as diols, which are characterized by the presence of two hydroxyl (-OH) groups. It is synthesized through selective processes that can affect its stereochemistry and functional properties.
  • Pharmaceutical Potential: Compounds with similar structures have been explored for their biological activity. The presence of a chlorophenyl group can enhance specific interactions within biological systems, making it a candidate for medicinal chemistry research.
  • Chirality: The presence of two chiral centers in this molecule allows for the existence of multiple stereoisomers. This chirality can significantly influence the compound's biological activity and interaction with enzymes, potentially leading to diverse therapeutic effects.
  • Pesticidal Properties: Due to the chlorinated aromatic component, similar compounds have been investigated for their pesticidal properties. The chlorophenyl moiety can sometimes impart effective biological activity against pests.

As a fascinating subject of study, 2-(3-Chlorophenyl)-3-methyl-butane-2,3-diol represents a unique intersection of synthetic organic chemistry and potential pharmaceutical application. Understanding its properties and behaviors could pave the way for future innovations in drug discovery and agrochemicals.

Synonyms
Metaglycodol
13980-94-4
Metaglicodol
Metaglycodol [INN]
Metaglycodolum
Lilly 26475
2-(3-chlorophenyl)-3-methylbutane-2,3-diol
2-(m-Chlorophenyl)-3-methyl-2,3-butanediol
NSC-169457
F72B92ZZ08
Metaglicodol [INN-Spanish]
Metaglycodolum [INN-Latin]
NSC 169457
UNII-F72B92ZZ08
2-m-Chlorophenyl-3-methyl-2,3-butanediol
2,3-Butanediol, 2-(3-chlorophenyl)-3-methyl-
2,3-BUTANEDIOL, 2-(m-CHLOROPHENYL)-3-METHYL-
SCHEMBL2108213
CHEMBL2105179
DTXSID70864459
WLN: QX1&1&XQ1&R CG
2, 2-(m-chlorophenyl)-3-methyl-
2, 2-(3-chlorophenyl)-3-methyl-
NSC169457
NS00124101
Q19597864