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3-Chlorophenylacetic acid

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Identification
Molecular formula
C8H7ClO2
CAS number
1878-66-6
IUPAC name
2-(3-chlorophenyl)acetic acid
State
State

The compound is typically found as a solid at room temperature.

Melting point (Celsius)
71.00
Melting point (Kelvin)
344.00
Boiling point (Celsius)
294.00
Boiling point (Kelvin)
567.00
General information
Molecular weight
170.59g/mol
Molar mass
170.5860g/mol
Density
1.3140g/cm3
Appearence

3-Chlorophenylacetic acid appears as white to off-white crystalline powder.

Comment on solubility

Solubility of 2-(3-chlorophenyl)acetic acid

2-(3-chlorophenyl)acetic acid, a compound with interesting properties, exhibits moderate solubility in various solvents. Here are some key points about its solubility characteristics:

  • Aqueous Solubility: The compound is sparingly soluble in water, which is typical for many carboxylic acids due to hydrogen bonding capabilities.
  • Organic Solvent Solubility: It is more soluble in organic solvents such as ethanol, acetone, and dichloromethane. This is attributed to its hydrophobic aromatic chlorophenyl group.
  • Temperature Dependency: The solubility of 2-(3-chlorophenyl)acetic acid can increase with temperature, so it is advisable to consider temperature when preparing solutions.

In summary, this compound displays a unique solubility profile that is influenced by the nature of the solvents and environmental conditions. Its moderate solubility in water and higher solubility in organic solvents makes it versatile for various applications in research and industry.

Interesting facts

Insights into 2-(3-Chlorophenyl)acetic Acid

2-(3-Chlorophenyl)acetic acid, a fascinating compound, offers numerous intriguing aspects worth exploring. This aromatic acetic acid derivative is notable not only for its chemical properties but also for its applications in various fields.

Key Characteristics:

  • Pharmaceutical Relevance: This compound is often used as an intermediate in the synthesis of numerous pharmaceuticals, particularly in the development of analgesics and anti-inflammatory medications.
  • Importance in Research: Scientists investigate 2-(3-chlorophenyl)acetic acid for its potential activities, including anti-inflammatory, analgesic, and antipyretic effects.
  • Structural Insights: The presence of the 3-chlorophenyl group enhances the compound's lipophilicity, which can affect its biological activity and solubility in biological systems.

Interesting Applications:

  • Drug Formulation: The compound can play a vital role in the design of controlled-release formulations due to its chemical stability.
  • Biological Studies: Research focused on its mechanism of action may lead to the discovery of new therapeutic targets for treating pain and inflammation.

In summary, 2-(3-chlorophenyl)acetic acid is not merely a chemical; it is a promising candidate with vast implications in medicinal chemistry. As research continues to unveil its complexities, this compound remains a focal point for chemists and pharmacologists alike, making it a delightful topic in the realm of chemistry.

Synonyms
3-CHLOROPHENYLACETIC ACID
1878-65-5
2-(3-chlorophenyl)acetic acid
m-Chlorophenylacetic acid
Benzeneacetic acid, 3-chloro-
3-Chlorobenzeneacetic acid
Acetic acid, (m-chlorophenyl)-
(m-Chlorophenyl)acetic acid
(3-chlorophenyl)acetic acid
F3JK7EW3SX
EINECS 217-520-0
NSC 87556
NSC-87556
DTXSID5075151
BENZENEACETIC ACID, M-CHLORO-
CHEMBL-335792
DTXCID3035925
Benzeneacetic acid, 3-chloro-(9CI)
Acetic acid, (m-chlorophenyl)-(8CI)
217-520-0
inchi=1/c8h7clo2/c9-7-3-1-2-6(4-7)5-8(10)11/h1-4h,5h2,(h,10,11
MFCD00004332
3-chlorophenyl acetic acid
(3-Chloro-phenyl)-acetic acid
3-Chlorophenylaceticacid
Meta-chlorophenyl acetic acid
UNII-F3JK7EW3SX
3-chloro-phenylacetic acid
3-chlorophenyl-acetic acid
(3-chlorophenyl)-acetic acid
SCHEMBL467923
CHEMBL335792
2-(3-chlorophenyl) acetic acid
3-Chlorophenylacetic acid, 98%
acetic acid, 2-(3-chlorophenyl)-
NSC87556
STL169032
AKOS000155364
AB00363
AC-3240
CS-W010777
FC12120
PS-5572
SY004837
DB-304626
C1055
NS00026139
EN300-64105
AC-509/25001994
Q63395571
m-Chlorophenylacetic acid;2-(3-chlorophenyl)acetic acid
Z285184608