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Etomidate

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Identification
Molecular formula
C11H13ClN2S
CAS number
33125-97-2
IUPAC name
2-[(3-chlorophenyl)methylsulfanyl]-4,5-dihydro-1H-imidazole
State
State

Etomidate is typically found as a solid at room temperature.

Melting point (Celsius)
166.00
Melting point (Kelvin)
439.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
244.75g/mol
Molar mass
244.7460g/mol
Density
1.1900g/cm3
Appearence

Etomidate is a white crystalline powder. It is odorless.

Comment on solubility

Solubility of 2-[(3-chlorophenyl)methylsulfanyl]-4,5-dihydro-1H-imidazole

The solubility of 2-[(3-chlorophenyl)methylsulfanyl]-4,5-dihydro-1H-imidazole is influenced by various factors including its molecular structure and functional groups. This compound, with its unique imidazole framework, presents an interesting case for solubility behavior.

  • Polarity: The presence of a chlorophenyl group may enhance the molecule's polarity, potentially affecting its solubility in polar solvents.
  • Hydrophobic Interactions: The methylsulfanyl substituent could contribute to hydrophobic characteristics, which might limit solubility in aqueous solutions.
  • Solvent Compatibility: It is anticipated that 2-[(3-chlorophenyl)methylsulfanyl]-4,5-dihydro-1H-imidazole would be more soluble in organic solvents like ethanol or methanol compared to water.

In conclusion, while the specific solubility values may vary, understanding the underlying chemical interactions provides valuable insights. It’s often said that “like dissolves like,” highlighting that the solubility of this compound is expected to favor organic solvents due to its structural characteristics. Further empirical studies would elucidate its exact solubility profile.

Interesting facts

Exciting Insights into 2-[(3-chlorophenyl)methylsulfanyl]-4,5-dihydro-1H-imidazole

2-[(3-chlorophenyl)methylsulfanyl]-4,5-dihydro-1H-imidazole is a unique hybrid compound that bridges various fields of chemistry and medicinal applications. Below are some fascinating aspects of this compound:

  • Structural Diversity: The compound features a complex imidazole ring fused with a sulfur moiety, imparting it with interesting chemical properties that make it a subject of study in both organic and medicinal chemistry.
  • Pharmacological Potentials: Compounds containing imidazole rings are well-known for their versatility in pharmaceutical applications. They are often explored as potential anti-cancer, anti-inflammatory, or anti-microbial agents.
  • Chlorine's Role: The presence of the 3-chlorophenyl group is significant as chlorine substituents can enhance biological activities and compound stability. This is often referred to as the 'halogen effect' in drug design.
  • Mechanistic Insights: Understanding the reaction mechanisms involving this compound can yield insights into its reactivity and potential as a precursor in synthetic organic chemistry.
  • Synthetic Route: The synthesis of compounds like this often involves multi-step processes and can serve as an exercise in learning various organic synthesis techniques, such as nucleophilic substitutions and cyclizations.

As researchers delve deeper into its properties, 2-[(3-chlorophenyl)methylsulfanyl]-4,5-dihydro-1H-imidazole serves as a reminder of the intricate relationship between structure and functionality in chemistry. As one student put it, "The amalgamation of diverse elements within a single molecule can lead to extraordinary potential in the realm of medicinal applications."


Synonyms
NCIOpen2_008415
SCHEMBL5732708
2-{[(3-chlorophenyl)methyl]sulfanyl}-4,5-dihydro-1H-imidazole
AKOS005208237
CCG-256409
EN300-241975
712254-83-6