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Diethylaminoacetyl-ethoxyphenylhydrazide

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Identification
Molecular formula
C15H23N3O2
CAS number
31035-31-1
IUPAC name
2-[3-(diethylaminomethyl)-4-ethoxy-phenyl]acetohydrazide
State
State

This compound is typically a solid at room temperature, presenting a crystalline form. It is not very volatile under standard conditions.

Melting point (Celsius)
147.00
Melting point (Kelvin)
420.15
Boiling point (Celsius)
403.50
Boiling point (Kelvin)
676.60
General information
Molecular weight
280.37g/mol
Molar mass
280.3740g/mol
Density
1.1600g/cm3
Appearence

This compound appears as a white to off-white crystalline powder. Its appearance reflects its solid state at room temperature and typical crystalline structure associated with many organic compounds of similar composition.

Comment on solubility

Solubility of 2-[3-(diethylaminomethyl)-4-ethoxy-phenyl]acetohydrazide

The solubility of 2-[3-(diethylaminomethyl)-4-ethoxy-phenyl]acetohydrazide in various solvents is an important aspect to consider when investigating its potential applications and behavior in different environments.

This compound is characterized by its organic nature, which suggests a variable solubility pattern. Typically, hydrazides exhibit moderate to high solubility in:

  • Alcohols (e.g., methanol, ethanol) due to the capability of hydrogen bonding.
  • Apolar solvents like chloroform, but this can vary based on the structural features of the compound.
  • Aqueous solutions may show limited solubility because of its hydrophobic groups.

Factors influencing the solubility include:

  • Functional groups present in the compound (e.g., ethoxy and diethylamino).
  • Molecular interactions, such as hydrogen bonding and van der Waals forces.
  • Temperature and pH of the solution.

In practice, it is often observed that:

  • The polar nature of alcohols enhances solubility.
  • The introduction of diethylamino groups may improve solubility in organic solvents.

Understanding these solubility characteristics is crucial for formulating effective applications and enhances the overall utility of this compound in chemical processes and potential pharmaceutical contexts.

Interesting facts

Interesting Facts about 2-[3-(diethylaminomethyl)-4-ethoxy-phenyl]acetohydrazide

2-[3-(diethylaminomethyl)-4-ethoxy-phenyl]acetohydrazide is a fascinating compound that draws attention not only for its structural complexity but also for its potential applications in various scientific fields. Below are some intriguing aspects of this compound:

  • Synthetic Versatility: This compound can be synthesized through various methods, making it a valuable subject of study for chemists interested in organic synthesis techniques.
  • Biological Activity: Compounds with hydrazide functional groups are known for their intriguing biological activities, ranging from antimicrobial to anti-inflammatory effects. Researchers are excited about exploring the pharmacological properties of this particular compound.
  • Structure-Activity Relationship (SAR): The presence of a diethylaminomethyl group alongside ethoxy substitution on the phenyl ring provides opportunities to investigate how modifications to the structure can affect the compound's biological efficacy.
  • Application in Drug Development: Due to its unique architecture, this compound is of interest in drug discovery, particularly for developing new therapeutics with enhanced specificity and reduced side effects.
  • Research Potential: The intriguing properties and activities of hydrazide-containing compounds like this one offer numerous research avenues in medicinal chemistry, leading to the development of new drugs and therapeutic agents.

In summary, 2-[3-(diethylaminomethyl)-4-ethoxy-phenyl]acetohydrazide is representative of the breadth and depth of organic synthesis and medicinal chemistry, illustrating how small changes in molecular structure can yield valuable insights into biological activity and therapeutic potential.

Synonyms
29076-35-5
ACETIC ACID, (alpha-(DIETHYLAMINO)-4-ETHOXY-m-TOLYL)-, HYDRAZIDE
3-((Diethylamino)methyl)-4-ethoxybenzeneacetic acid hydrazide
BRN 2873024
Benzeneacetic acid, 3-((diethylamino)methyl)-4-ethoxy-, hydrazide
DTXSID40183321