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Difenamizole

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Identification
Molecular formula
C16H25N3O2
CAS number
55972-43-5
IUPAC name
2-[3-(diethylaminomethyl)-4-isopropoxy-phenyl]acetohydrazide
State
State

The compound is a solid under room temperature conditions. Its crystalline form allows it to be handled in the pharmaceutical manufacturing process with ease.

Melting point (Celsius)
159.00
Melting point (Kelvin)
432.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
291.39g/mol
Molar mass
291.3850g/mol
Density
1.1450g/cm3
Appearence

Difenamizole typically appears as a crystalline solid. It might be white to off-white in color and is generally distributed in powder or solid form for pharmaceutical purposes.

Comment on solubility

Solubility of 2-[3-(diethylaminomethyl)-4-isopropoxy-phenyl]acetohydrazide

The solubility of 2-[3-(diethylaminomethyl)-4-isopropoxy-phenyl]acetohydrazide is influenced by several factors due to its complex molecular structure. Understanding its solubility is essential for predicting its behavior in various chemical environments.

Factors Affecting Solubility:

  • Polarity: The presence of diethylamine and isopropoxy groups suggests a mix of both polar and non-polar characteristics, impacting solubility in different solvents.
  • Hydrogen Bonding: The hydrazide functional group can participate in hydrogen bonding, which may aid its solubility in polar solvents like water.
  • Temperature: As with many organic compounds, increased temperature generally enhances solubility.

In practical terms, the compound may exhibit solubility in:

  • Apolar Solvents: It could possibly dissolve in organic solvents such as ethanol or acetone due to its hydrophobic hydrocarbon chains.
  • Polar Solvents: Limited solubility might be observed in water, owing to the presence of polar -NH and -O functionalities, but might require a specific pH or ionic conditions to enhance solubility.

In summary, the solubility of 2-[3-(diethylaminomethyl)-4-isopropoxy-phenyl]acetohydrazide is a nuanced topic due to the interplay of its molecular features. As always, *experimental data* would be valuable to confirm these predictions and guide practical applications.

Interesting facts

Interesting Facts about 2-[3-(diethylaminomethyl)-4-isopropoxy-phenyl]acetohydrazide

2-[3-(diethylaminomethyl)-4-isopropoxy-phenyl]acetohydrazide is a remarkable chemical compound that showcases the fascinating intersection of organic chemistry and medicinal applications. This compound belongs to the class of hydrazides, which are known for their significant biological activities. Its unique structure contributes to various properties that are intriguing for both scientists and pharmacologists alike.

Key Highlights

  • Biological Activity: Hydrazide derivatives have been studied extensively for their potential therapeutic properties, including anti-tuberculosis and anti-cancer activities. This compound might also exhibit similar characteristics, attracting interest for drug discovery.
  • Functional Groups: The presence of diethylamino and isopropoxy groups enhances the lipophilicity of the molecule, which can improve its permeability through biological membranes. This quality is crucial in drug design.
  • Synthetic Versatility: The synthesis of hydrazides like this one often involves straightforward reactions between hydrazines and carboxylic acids, making them accessible for further functionalization. This allows for the customization of properties for specific applications.
  • Potential Research Applications: The compound's structure offers ample opportunities for medicinal chemistry research, particularly in the areas of developing new pharmaceuticals and understanding the mechanisms of action of similar compounds.

As emphasized by renowned chemists, "The future of drug discovery lies in understanding molecular interactions." This quote underlines the importance of compounds such as 2-[3-(diethylaminomethyl)-4-isopropoxy-phenyl]acetohydrazide in enhancing our understanding of molecular behavior and improving therapeutic outcomes. The ongoing exploration of such compounds may lead to breakthroughs in treating various diseases.

In conclusion, 2-[3-(diethylaminomethyl)-4-isopropoxy-phenyl]acetohydrazide is more than just a chemical entity; it represents a promising avenue for future research and development in pharmacology and medicinal chemistry.

Synonyms
PJY9DC7YCL
BRN 2874261
29076-37-7
ACETIC ACID, (alpha-(DIETHYLAMINO)-4-ISOPROPOXY-m-TOLYL)-, HYDRAZIDE
Benzeneacetic acid, 3-((diethylamino)methyl)-4-(1-methylethoxy)-, hydrazide
DTXSID60183323
3-((Diethylamino)methyl)-4-(1-methylethoxy)benzeneacetic acid hydrazid
2-[3-(diethylaminomethyl)-4-propan-2-yloxyphenyl]acetohydrazide
2-(3-(DIETHYLAMINOMETHYL)-4-PROPAN-2-YLOXYPHENYL)ACETOHYDRAZIDE
DIETHYLAMINO)METHYL)-4-(1-METHYLETHOXY)BENZENEACETIC ACID HYDRAZIDE, 3-((
RefChem:108884
DTXCID70105814
UNII-PJY9DC7YCL
3-((DIETHYLAMINO)METHYL)-4-(1-METHYLETHOXY)BENZENEACETIC ACID HYDRAZIDE