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Lodocaine

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Identification
Molecular formula
C14H22N2O2
CAS number
137-58-6
IUPAC name
2-[3-(diethylaminomethyl)-4-methoxy-phenyl]acetohydrazide
State
State

At room temperature, lidocaine is commonly encountered as a solid in the form of a white powder.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
235.34g/mol
Molar mass
235.3360g/mol
Density
1.0840g/cm3
Appearence

Lidocaine appears as a white or slightly yellowish crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 2-[3-(diethylaminomethyl)-4-methoxy-phenyl]acetohydrazide

The solubility of 2-[3-(diethylaminomethyl)-4-methoxy-phenyl]acetohydrazide can be influenced by various factors such as temperature, pH, and the presence of other solvents. This compound exhibits a unique combination of functional groups which can alter its interaction with solvents.

Factors Influencing Solubility

  • Polarity: The presence of polar groups in the compound can enhance its solubility in polar solvents, while non-polar characteristics may promote solubility in organic solvents.
  • Temperature: Generally, an increase in temperature tends to enhance solubility for many compounds, making it essential to consider when dissolving.
  • pH Levels: As a hydrazide, the pH of the solution can significantly impact its ionization, thereby affecting its solubility properties.

It is important to note that while the compound may show good solubility in dimethyl sulfoxide (DMSO) and ethanol, it might have limited solubility in less polar solvents such as hexane. Therefore, to determine the precise solubility characteristics of 2-[3-(diethylaminomethyl)-4-methoxy-phenyl]acetohydrazide, conducting thorough solubility tests in various solvents is highly recommended.

In conclusion, the solubility of this compound is a function of its chemical structure and environmental factors, emphasizing the importance of adapting experimental conditions accordingly for successful application.

Interesting facts

Interesting Facts about 2-[3-(diethylaminomethyl)-4-methoxy-phenyl]acetohydrazide

2-[3-(diethylaminomethyl)-4-methoxy-phenyl]acetohydrazide is a fascinating compound that showcases the intricate relationship between molecular structure and biological activity. This compound belongs to the class of hydrazides, which are known for their diverse roles in pharmacology.

Key Highlights:

  • Pharmaceutical Importance: It is often explored for its potential as a therapeutic agent in the treatment of various ailments, particularly due to the presence of the hydrazide functional group, which has been linked to anti-tumor and antimicrobial properties.
  • Structure-Activity Relationship: The unique combination of a diethylaminomethyl substituent and a methoxy group can significantly influence the compound's interaction with biological targets, making it a subject of interest in medicinal chemistry.
  • Chemical Versatility: The hydrazide group allows for numerous chemical modifications that can enhance efficacy or selectivity, demonstrating the compound's adaptability for research in drug design.
  • Mechanisms of Action: Understanding how this compound interacts at the molecular level can provide insights into its pharmacological effects, including possible mechanisms of action against cancer cells or bacteria.

As a chemistry student or a researcher, investigating 2-[3-(diethylaminomethyl)-4-methoxy-phenyl]acetohydrazide offers a rich opportunity to delve into the complexities of organic synthesis, the therapeutic potential of hydrazides, and the significance of structure in drug development. The phrase "The right structure can make all the difference" certainly holds true in the realm of medicinal chemistry.

In conclusion, while 2-[3-(diethylaminomethyl)-4-methoxy-phenyl]acetohydrazide may not be the most well-known compound, its molecular intricacies and potential applications make it a worthy topic of exploration in the field of chemical research.

Synonyms
29076-33-3
ACETIC ACID, (alpha-(DIETHYLAMINO)-4-METHOXY-m-TOLYL)-, HYDRAZIDE
3-((Diethylamino)methyl)-4-methoxy-benzeneacetic acid hydrazide
BRN 2871620
Benzeneacetic acid, 3-((diethylamino)methyl)-4-methoxy-, hydrazide
DTXSID80183320