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Carvedilol

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Identification
Molecular formula
C24H26ClNO4
CAS number
72956-09-3
IUPAC name
2-(3-ethoxycarbonyl-1,2-dimethyl-indol-5-yl)oxyethyl-diethyl-ammonium;chloride
State
State

At room temperature, Carvedilol is in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
114.00
Melting point (Kelvin)
387.15
Boiling point (Celsius)
332.50
Boiling point (Kelvin)
605.65
General information
Molecular weight
406.93g/mol
Molar mass
406.5000g/mol
Density
1.2000g/cm3
Appearence

Carvedilol is typically a white to off-white crystalline powder. It is relatively sparingly soluble in water but freely soluble in ethanol.

Comment on solubility

Solubility of 2-(3-ethoxycarbonyl-1,2-dimethyl-indol-5-yl)oxyethyl-diethyl-ammonium;chloride

This compound, with its complex structure, exhibits interesting solubility characteristics that can be influenced by various factors. The presence of both ethoxycarbonyl and quaternary ammonium groups suggests a certain degree of polarity, which may enhance solubility in polar solvents. Here are a few key points regarding its solubility:

  • Polar Solvents: This compound is likely to be soluble in solvents such as water and alcohols due to its quaternary ammonium component, which tends to interact favorably with polar molecules.
  • Non-Polar Solvents: Solubility in non-polar solvents (e.g., hexane or chloroform) is expected to be quite limited because of the polar functional groups in the structure.
  • Temperature Dependence: The solubility may increase with temperature, a common trait for many chemical compounds, as higher temperatures can promote molecular interactions.
  • pH Influence: Changes in pH could affect the ionization of the ammonium group, thus altering solubility; neutral pH tends to be more favorable for solubility.

In summary, the solubility behavior of 2-(3-ethoxycarbonyl-1,2-dimethyl-indol-5-yl)oxyethyl-diethyl-ammonium;chloride is shaped not only by its molecular structure but also by the environment in which it is placed. Understanding these aspects is crucial for applications in various fields, including pharmaceuticals and material science.

Interesting facts

Interesting Facts about 2-(3-ethoxycarbonyl-1,2-dimethyl-indol-5-yl)oxyethyl-diethyl-ammonium chloride

This compound, with a rather complex name, belongs to a class of quaternary ammonium salts, which are known for their versatile applications in various fields, including chemistry, pharmaceuticals, and materials science. Here are some significant aspects to consider:

  • Quaternary Ammonium Compounds: The presence of a quaternary ammonium group makes this compound a potent surfactant. Quaternary ammonium compounds are often used in disinfectants, fabric softeners, and in pharmaceutical formulations due to their ability to interact with biological membranes.
  • Indole Derivatives: The incorporation of an indole moiety in this structure is particularly intriguing. Indoles are key components in numerous natural products and have been identified as important pharmacophores in medicinal chemistry. They exhibit various biological activities, including anti-inflammatory and anti-cancer properties.
  • Ethoxycarbonyl Group: The ethoxycarbonyl group contributes significantly to the compound's solubility and reactivity. Functional groups like this one can modulate the physicochemical properties of a compound, facilitating its use in different environments and applications.
  • Pharmaceutical Potential: Compounds with complex architectures often exhibit enhanced biological activities. Researchers are actively investigating the medicinal chemistry of such molecules, aiming to discover new therapeutic agents with improved efficacy and reduced side effects.

In essence, the compound 2-(3-ethoxycarbonyl-1,2-dimethyl-indol-5-yl)oxyethyl-diethyl-ammonium chloride highlights the intricate relationship between chemical structure and function. Understanding these connections is crucial for innovation in drug design and material development. As stated by a renowned chemist, “In the realm of molecules, complexity can lead to unexpected wonders.”

Synonyms
Of-2438
18235-89-7
OF 2438
Indole-3-carboxylic acid, 5-(2-(diethylamino)ethoxy)-1,2-dimethyl-, ethyl ester, monohydrochloride