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Tropisetron hydrochloride

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Identification
Molecular formula
C17H21ClN2O2
CAS number
105826-92-4
IUPAC name
2-(3-ethoxycarbonyl-5-methoxy-1-methyl-indol-2-yl)ethyl-dimethyl-ammonium;chloride
State
State

Tropisetron hydrochloride is typically in a solid state at room temperature.

Melting point (Celsius)
189.00
Melting point (Kelvin)
462.15
Boiling point (Celsius)
305.20
Boiling point (Kelvin)
578.35
General information
Molecular weight
320.82g/mol
Molar mass
0.0000g/mol
Density
1.2200g/cm3
Appearence

Tropisetron hydrochloride usually appears as a white crystalline powder. It is known for its high purity and fine texture, which is typical for pharmaceutical-grade chemical compounds.

Comment on solubility

Solubility of 2-(3-ethoxycarbonyl-5-methoxy-1-methyl-indol-2-yl)ethyl-dimethyl-ammonium Chloride

The solubility of the compound 2-(3-ethoxycarbonyl-5-methoxy-1-methyl-indol-2-yl)ethyl-dimethyl-ammonium chloride can be assessed by examining several key factors:

  • Polarity: This compound features charged ammonium ions due to the dimethylammonium group, suggesting a higher solubility in polar solvents, particularly water.
  • Aromatic Substitution: The indole structure and the presence of ethoxy and methoxy groups can also influence its solubility characteristics. These groups might enhance solubility due to their ability to form hydrogen bonds with the solvent.
  • pH Influence: Being a quaternary ammonium salt, the solubility is generally less affected by pH; however, extreme pH conditions could impact its stability and solubility.
  • Concentration Effects: At high concentrations, precipitation might occur due to ionic interactions. It’s important to consider the solubility limits when preparing solutions.

In summary, 2-(3-ethoxycarbonyl-5-methoxy-1-methyl-indol-2-yl)ethyl-dimethyl-ammonium chloride is expected to be highly soluble in polar solvents like water and potentially in some organic solvents, making it versatile for various applications in chemical formulations.

Interesting facts

Interesting Facts about 2-(3-Ethoxycarbonyl-5-methoxy-1-methyl-indol-2-yl)ethyl-dimethyl-ammonium;chloride

This intriguing compound brings together various chemical functionalities, highlighting the beauty of organic synthesis. Here are some remarkable aspects that make this compound noteworthy:

  • Versatile Applications: The compound's structure suggests potential use in pharmaceuticals, particularly in drug design and development due to the presence of indole, which is known for its biological activity.
  • Indole Importance: Indole derivatives have been found in numerous natural products and pharmaceutical agents, making this compound a point of interest for medicinal chemists.
  • Chloride Salts: The chloride component can enhance the solubility and bioavailability of the indole derivative, facilitating its use in various applications ranging from agricultural to medicinal fields.
  • Structure-Activity Relationship (SAR): Understanding how modifications to the indole ring affect biological activity is critical; thus, studying this compound can provide insights into SAR.
  • Natural Inspirations: The design of this compound may have been inspired by natural alkaloids, which often possess complex structures and exhibit significant pharmacological properties.
  • Innovation in Synthesis: The synthesis of such compounds often involves advanced techniques in organic chemistry, paving the way for students and scientists to explore innovative pathways in compound construction.

In summary, 2-(3-ethoxycarbonyl-5-methoxy-1-methyl-indol-2-yl)ethyl-dimethyl-ammonium;chloride exemplifies the intersection of synthetic chemistry and biological potential, making it an exciting topic for further study and exploration.

Synonyms
Of-2434
18235-85-3
OF 2434
Indole-3-carboxylic acid, 2-(2-(dimethylamino)ethyl)-5-methoxy-1-methyl-, ethyl ester, monohydrochloride