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Etomidate hydrochloride

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Identification
Molecular formula
C14H18ClN3O2
CAS number
135861-58-2
IUPAC name
2-(3-ethoxycarbonyl-5-methoxy-2-methyl-indol-1-yl)ethyl-diethyl-ammonium;chloride
State
State
At room temperature, Etomidate hydrochloride is in a solid state, appearing as a crystalline powder.
Melting point (Celsius)
147.00
Melting point (Kelvin)
420.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
308.79g/mol
Molar mass
308.7890g/mol
Density
1.1186g/cm3
Appearence
Etomidate hydrochloride appears as a white to off-white crystalline powder. It is odorless and has a slightly bitter taste. As a compound, it is sensitive to light and should be stored away from direct exposure.
Comment on solubility

Solubility Characteristics of 2-(3-ethoxycarbonyl-5-methoxy-2-methyl-indol-1-yl)ethyl-diethyl-ammonium;chloride

The solubility of 2-(3-ethoxycarbonyl-5-methoxy-2-methyl-indol-1-yl)ethyl-diethyl-ammonium;chloride, a quaternary ammonium salt, can be influenced by various factors including its ionic character and the surrounding environment. Understanding its solubility is essential for applications in both laboratory settings and industrial processes.

Key Points on Solubility:

  • Solvent Polarity: As a chloride salt, this compound is expected to be soluble in polar solvents such as water due to its ionic nature.
  • Concentration: Its solubility may vary with concentration; higher concentrations may lead to saturation in the solution.
  • Temperature Sensitivity: Increasing the temperature often enhances solubility, especially for ionic compounds.
  • pH Levels: The solubility can be affected by the pH of the solution, particularly if the compound has functional groups that can be protonated or deprotonated.
  • Structural Considerations: The presence of ethoxycarbonyl and methoxy substituents may influence solubility due to their hydrophilic properties.

In summary, while 2-(3-ethoxycarbonyl-5-methoxy-2-methyl-indol-1-yl)ethyl-diethyl-ammonium;chloride can be anticipated to demonstrate significant solubility in polar solvents, the specific conditions and structural nuances should always be considered when predicting its behavior in different environments.

Interesting facts

Interesting Facts about 2-(3-Ethoxycarbonyl-5-methoxy-2-methyl-indol-1-yl)ethyl-diethyl-ammonium; chloride

This intriguing compound is a member of the indole derivatives, which are a class of compounds known for their diverse biological activities. Here are some fascinating aspects about this compound:

  • Biological Significance: Indole derivatives have been extensively studied for their roles in medicinal chemistry, particularly for their potential anti-cancer, anti-inflammatory, and anti-oxidative properties.
  • Structure-Activity Relationship: The specific substitution patterns on the indole ring influence not only the biological activity of the compound but also its pharmacokinetic properties. For example, the ethoxycarbonyl and methoxy groups can enhance solubility and modulate binding affinity to biological targets.
  • Quaternary Ammonium Structure: As it contains a quaternary ammonium moiety, this compound can interact with biological membranes, which may allow for unique mechanisms of action in drug delivery systems.
  • Versatile Synthesis: Compounds like this can often be synthesized through multi-step reactions, showcasing the elegance and complexity of organic synthesis in generating targeted pharmacophores.
  • Potential in Drug Development: Due to its structural features, this compound represents a promising candidate for drug development, especially in the context of targeting specific biological pathways.

In summary, 2-(3-Ethoxycarbonyl-5-methoxy-2-methyl-indol-1-yl)ethyl-diethyl-ammonium; chloride exemplifies the intricate relationship between molecular structure and biological function, making it a valuable compound for further research in medicinal chemistry.

Synonyms
Of-2439
18235-86-4
OF 2439
Indole-3-carboxylic acid, 1-(2-(diethylamino)ethyl)-5-methoxy-2-methyl-, ethyl ester, monohydrochloride