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Isoquinoline derivative hydrochloride

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Identification
Molecular formula
C14H20ClNO2S
CAS number
not available
IUPAC name
2-(3-ethylsulfinylpropyl)-3,4-dihydro-1H-isoquinoline;hydrochloride
State
State

At room temperature, this compound is in a solid state, typically forming a crystalline solid. The hydrochloride form can influence its stability and solubility properties.

Melting point (Celsius)
202.00
Melting point (Kelvin)
475.00
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.00
General information
Molecular weight
273.83g/mol
Molar mass
273.8260g/mol
Density
1.2360g/cm3
Appearence

This compound typically appears as a white to off-white crystalline powder. The hydrochloride form may cause it to be more hygroscopic, potentially absorbing moisture from the air, which can lead to clumping or solidification over time if not stored properly.

Comment on solubility

Solubility of 2-(3-ethylsulfinylpropyl)-3,4-dihydro-1H-isoquinoline; hydrochloride

The solubility of 2-(3-ethylsulfinylpropyl)-3,4-dihydro-1H-isoquinoline; hydrochloride plays a crucial role in its applications and efficacy. When discussing the solubility of this compound, several factors come into play:

  • Polarity: The presence of the hydrochloride group enhances the compound's polarity, which typically results in better solubility in polar solvents such as water.
  • Temperature Influence: Increased temperature often leads to higher solubility for many compounds; thus, experiments at varying temperatures can provide insight into optimal conditions.
  • pH Dependence: Being a salt, the solubility can be affected by the pH of the solution. Variations in pH can lead to ionization changes that may enhance or reduce solubility.

In practical applications, in vitro studies may reveal significant information about the solubility profile, which is vital for pharmacokinetics. Moreover, as with many hydrochloride salts, dissolution in aqueous solutions is often favorable, potentially facilitating its use in formulations.

Understanding the solubility characteristics of this compound can be summarized by considering the following points:

  1. Hydrochloride salts generally exhibit good solubility in water.
  2. Experimental determination of solubility under various conditions is essential for accurate application.
  3. Increased solubility often correlates with improved bioavailability in biological systems.

Thus, the solubility of 2-(3-ethylsulfinylpropyl)-3,4-dihydro-1H-isoquinoline; hydrochloride is both an intriguing and essential aspect for researchers and practitioners working with this compound.

Interesting facts

Interesting Facts about 2-(3-Ethylsulfinylpropyl)-3,4-dihydro-1H-isoquinoline; Hydrochloride

This unique compound belongs to a class of chemicals known as isoquinolines, which are known for their diverse biological activities. Here are some fascinating insights about it:

  • Biological Significance: Isoquinolines, including this compound, often exhibit significant pharmacological properties. They are studied for their potential use in treating various medical conditions, from neurodegenerative diseases to cancer.
  • Structural Diversity: The intricate structure of this compound features a sulfinyl group, which can enhance its reactivity and pharmacological efficacy, making it a subject of interest in medicinal chemistry.
  • Synthetic Pathways: The synthesis of isoquinolines often involves complex chemical reactions, highlighting a range of techniques in organic synthesis which may include cyclization, oxidation, and reduction.
  • Research Potential: Compounds like this one are frequently explored in academic research for their potential in drug design, particularly due to their ability to interact with biological targets.
  • Therapeutic Uses: Preliminary studies suggest that derivatives of isoquinoline compounds can have anti-inflammatory, anti-bacterial, and anti-anxiety effects.

As we continue to explore the vast realm of organic chemistry, understanding the properties and implications of compounds such as 2-(3-ethylsulfinylpropyl)-3,4-dihydro-1H-isoquinoline; hydrochloride can lead to exciting advancements in therapeutic applications. Each new finding may open doors to novel medicinal possibilities.

Synonyms
Esproquin hydrochloride
Esproquin HCl
23486-22-8
Esproquine hydrochloride
NC-7197
NSC-84974
1P9E5C9137
RefChem:137888
Esproquin hydrochloride [USAN]
Isoquinoline, 2-(3-(ethylsulfinyl)propyl)-1,2,3,4-tetrahydro-, hydrochloride
Esproquin hydrochloride (USAN)
2-(3-ethylsulfinylpropyl)-3,4-dihydro-1H-isoquinoline;hydrochloride
NSC 84974
NC 7197
UNII-1P9E5C9137
2-(3-(Ethylsulfinyl)propyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride
SCHEMBL120659
CHEMBL2106234
NSC84974
ISOQUINOLINE, 1,2,3,4-TETRAHYDRO-2-(3-(ETHYLSULFINYL)PROPYL)-, HYDROCHLORIDE
D04058
Q27252715
2-[3-(ethylsulfinyl)propyl]-1,3,4-tetrahydroisoquinoline hydrochloride
2-(3-ETHYLSULFINYLPROPYL)-1,2,3,4-TETRAHYDROISOQUINOLINE HYDROCHLORIDE
ISOQUINOLINE, 2-(3-(ETHYLSULFINYL)PROPYL)-1,2,3,4-TETRAHYDRO-, HYDROCHLORIDE (1:1)