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Silodosin

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Identification
Molecular formula
C25H36ClNO4Si
CAS number
160970-54-7
IUPAC name
2-[3-hydroxy-3-methyl-2-(4-trimethylsilylphenyl)butanoyl]oxyethyl-dimethyl-ammonium;chloride
State
State

At room temperature, Silodosin is typically found as a solid. This state facilitates its use in pharmaceutical formulations as it can be easily measured and incorporated into dosage forms.

Melting point (Celsius)
108.50
Melting point (Kelvin)
381.65
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
495.98g/mol
Molar mass
495.9820g/mol
Density
1.1000g/cm3
Appearence

The compound Silodosin typically appears as a white to off-white powder. It is crystalline in nature, providing a solid form that is easy to handle in its pure state.

Comment on solubility

Solubility of 2-[3-hydroxy-3-methyl-2-(4-trimethylsilylphenyl)butanoyl]oxyethyl-dimethyl-ammonium;chloride

The solubility of the compound 2-[3-hydroxy-3-methyl-2-(4-trimethylsilylphenyl)butanoyl]oxyethyl-dimethyl-ammonium;chloride can be influenced by several factors. Understanding these intricacies can help in determining its usage in various applications:

  • Polarity: This compound contains both polar and non-polar components. The presence of the quaternary ammonium group suggests a tendency towards solubility in polar solvents like water.
  • Hydrogen Bonding: The hydroxyl group in the structure enables the possibility of hydrogen bonding, which can significantly enhance solubility in polar media.
  • Silyl Group Effects: The presence of a trimethylsilyl group may influence solubility by providing lipophilic characteristics, potentially aiding the compound's dissolution in organic solvents.
  • Ionic Interactions: Being a quaternary ammonium salt, it is expected to be soluble in aqueous solutions, especially when countered with chloride anions which promote solubility due to their ability to stabilize ionic interactions.

Ultimately, the solubility of this compound can be summarized as:

  1. Generally soluble in polar solvents.
  2. Exhibits moderate solubility in aqueous solutions.
  3. Potential for increased solubility in organic solvents due to its unique structural components.

In conclusion, the solubility profile of 2-[3-hydroxy-3-methyl-2-(4-trimethylsilylphenyl)butanoyl]oxyethyl-dimethyl-ammonium;chloride is multifaceted, hinging on the balance between its polar and non-polar characteristics that invite exploration in different solvent environments.

Interesting facts

Interesting Facts About 2-[3-hydroxy-3-methyl-2-(4-trimethylsilylphenyl)butanoyl]oxyethyl-dimethyl-ammonium Chloride

This compound, often referred to in the scientific community for its complex molecular structure, showcases a fascinating interplay of organic chemistry and materials science. Its diverse functionalities are of particular interest, making it valuable in various applications.

Key Features

  • Ammonium Salt: Being a quaternary ammonium compound, it exhibits significant surface-active properties, which may enhance its performance in applications such as detergents and emulsifiers.
  • Hydroxyl Group: The presence of a hydroxyl group suggests that this compound can engage in hydrogen bonding, potentially impacting its behavior in biological and chemical interactions.
  • Trimethylsilyl Group: The incorporation of trimethylsilyl groups can improve the compound's stability and solubility in organic solvents, making it an intriguing subject for studies related to solvent systems.

As a scientist, one might find the following aspects particularly fascinating:

  • Complexity: The intricate structure offers insights into the synthesis of multifunctional compounds that can be utilized in pharmaceuticals and fine chemical manufacturing.
  • Biocompatibility: Compounds like this are often explored for their potential use in drug delivery systems due to their ability to modify cell membrane properties.
  • Research Applications: The compound's unique properties may have implications in the development of nanomaterials and surface coatings.

In summary, 2-[3-hydroxy-3-methyl-2-(4-trimethylsilylphenyl)butanoyl]oxyethyl-dimethyl-ammonium chloride stands as a remarkable example of how the combination of specific functional groups can lead to compounds with diverse and useful properties. As ongoing research continues to unravel its potential applications, it reinforces the significance of understanding chemical behavior at the molecular level.

Synonyms
20119-48-6
Butyric acid, 3-hydroxy-3-methyl-2-(p-(trimethylsilyl)phenyl)-, 2-(dimethylamino)ethyl ester, hydrochloride
3-Hydroxy-3-methyl-2-(p-(trimethylsilyl)phenyl)butyric acid 2-dimethylaminoethyl ester HCl
RefChem:331280