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Fluorescein

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Identification
Molecular formula
C20H10O5
CAS number
2321-07-5
IUPAC name
2-(3-hydroxy-6-oxo-xanthen-9-yl)benzoic acid
State
State

At room temperature, fluorescein is in a solid-state. It is typically a stable, crystalline powder that can be used and stored with relative ease in laboratory settings.

Melting point (Celsius)
314.00
Melting point (Kelvin)
587.15
Boiling point (Celsius)
596.00
Boiling point (Kelvin)
869.15
General information
Molecular weight
332.31g/mol
Molar mass
332.3130g/mol
Density
1.5800g/cm3
Appearence

Fluorescein is a bright orange/red powder that becomes intensely green fluorescent in alkaline solution. In its solid form, it can be described as a vibrant, crystalline powder, commonly used as a dye or a tracer.

Comment on solubility

Solubility of 2-(3-hydroxy-6-oxo-xanthen-9-yl)benzoic acid

The compound 2-(3-hydroxy-6-oxo-xanthen-9-yl)benzoic acid, with the molecular formula C20H10O5, exhibits notable solubility characteristics that are worth discussing. Generally, the solubility of a compound can be influenced by various factors such as its molecular structure, the presence of functional groups, and the solvent type.

Key Factors Influencing Solubility:

  • Molecular Structure: The presence of bulky aromatic rings and hydroxyl groups can affect the overall solubility.
  • Functional Groups: The carboxylic acid group (-COOH) is highly polar, which typically enhances solubility in polar solvents like water.
  • pH Dependence: The solubility of this compound may vary with pH, where deprotonation can increase its aqueous solubility.

In terms of solubility:

  • This compound is expected to be moderately soluble in polar organic solvents due to its functional groups.
  • It may exhibit limited solubility in non-polar solvents, making it less favorable for applications requiring such environments.

To summarize, the solubility profile of 2-(3-hydroxy-6-oxo-xanthen-9-yl)benzoic acid reflects its complex interplay of structural attributes and functional capabilities. Understanding these properties is crucial when considering practical applications in fields such as pharmaceuticals or material science.

Interesting facts

Interesting Facts about 2-(3-Hydroxy-6-oxo-xanthen-9-yl)benzoic Acid

2-(3-Hydroxy-6-oxo-xanthen-9-yl)benzoic acid, a fascinating compound, falls under the category of organic compounds that exhibit notable properties and diverse applications. Here are some intriguing aspects to consider:

  • Structural Characteristics: This compound is characterized by a combination of a xanthene moiety and a benzoic acid functional group. The presence of a hydroxyl group enhances its potential for reactivity and interaction with other molecules.
  • Photoactivity: Compounds like this one that contain chromophoric systems often exhibit interesting photophysical properties. They can absorb UV and visible light, making them valuable for applications in fluorescence and photodynamic therapy.
  • Clinical Relevance: The structural makeup suggests potential uses in medicinal chemistry. Derivatives of xanthene are known to be used in a range of biological applications, including as dyes and in the development of pharmaceuticals for treating various conditions.
  • Research Interest: This compound's unique structure makes it a subject of interest in materials science and organic synthesis. Researchers are exploring its potential use in organic light-emitting diodes (OLEDs) and as a dye in solar cells.
  • Environmental Significance: The presence of hydroxyl and carboxylic acid groups can increase the compound's solubility and reactivity in biological systems, paving the way for studies on its environmental impact and degradation pathways.

In summary, the exploration of 2-(3-hydroxy-6-oxo-xanthen-9-yl)benzoic acid is a gateway to understanding the intricate relationship between molecular structure and function, showcasing how such compounds can play vital roles in both scientific advancement and practical applications.

Synonyms
2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid
518-45-6
2-(3-hydroxy-6-oxoxanthen-9-yl)benzoic acid
Fluorescite
Funduscein-25
fluorescein (acid form)
2-(6-HYDROXY-3-OXO-3H-XANTHEN-9-YL)-BENZOIC ACID
CHEMBL177756
CHEBI:172923
2-(3-hydroxy-6-oxo-xanthen-9-yl)benzoic acid
2-(6-oxido-3-oxo-3H-xanthen-9-yl)benzoate
flourescein
1flr
1n0s
cid_3383
CBDivE_002901
SCHEMBL107875
Fluorescein (C.I. 45350)
DTXSID601031482
HMS3752I07
BBL002034
BDBM50143424
MFCD00066735
STK391288
AKOS000503167
TG2-210
NS-05493
NS00013513
EN300-172845
2-(3-hydroxy-6-keto-xanthen-9-yl)benzoic acid
2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoesaure
2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoicacid
2-(3-hydroxy-6-oxo-6H-xanthen-9-yl)benzoic acid
2-(6-Hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid #
3H-Xanthen-3-one, 6-hydroxy-10-[2-carboxyphenyl]-
Q27460338
3',6'-Dihydroxy-spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one
(3H)Xanthen-3-one, 10-deshydro-6-hydroxy-10-[2-carboxyphen-1-yl]-
3'',6''-dihydroxyspiro[1,3-dihydroisobenzofuran-1,9''-(9''H-xanthene)]-3-one